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      The Basic Science of Hair Biology

      research The Basic Science of Hair Biology

      29 citations , September 2012 in “Dermatologic Clinics”
      This article reviews the causal mechanisms of hair follicle disorders, focusing on inflammation, genetics, environment, and hormones, but it reports no new clinical results.
      Genetic Fate Mapping Using Site-Specific Recombinases

      research Genetic Fate Mapping Using Site-Specific Recombinases

      29 citations , January 2010 in “Methods in Enzymology”
      This review discusses five genetic fate mapping methods used to study cell behaviors during development and regeneration, detailing the necessary tools and considerations without reporting new experimental results.
      Parkinson's Disease and Skin Disorders: Non-Iatrogenic and Iatrogenic Connections

      research Parkinson's disease and skin

      28 citations , January 2021 in “Parkinsonism & related disorders (Online)/Parkinsonism & related disorders”
      This article reviews skin disorders in Parkinson's disease, highlighting the potential of skin studies and stem cell research to advance understanding and treatment of the neurodegenerative disorder, without presenting new results.
      Medication-Induced Repigmentation of Gray Hair: A Systematic Review

      research Medication-Induced Repigmentation of Gray Hair: A Systematic Review

      28 citations , December 2019 in “Skin appendage disorders”
      This review discusses medication-induced gray hair repigmentation, highlighting that certain anti-inflammatory drugs and melanogenesis stimulators can cause diffuse repigmentation, though evidence remains low-quality and these medications are not currently indicated for this purpose.
      Signaling by Senescent Melanocytes Hyperactivates Hair Growth

      research Signalling by senescent melanocytes hyperactivates hair growth

      27 citations , June 2023 in “Nature”
      In this study using genetic mouse models, researchers discovered that senescent melanocytes in nevi secrete osteopontin, which activates hair stem cells, enhancing hair growth; this process is mirrored in human hairy nevi, suggesting a potential therapeutic target for regenerative disorders.
      Insulin-Like Growth Factor-1: Roles in Androgenetic Alopecia

      research Insulin-like growth factor-1: roles in androgenetic alopecia

      27 citations , February 2014 in “Experimental Dermatology”
      This study found that dermal papilla cells from balding scalp follicles secrete significantly less insulin-like growth factor-1 and its binding proteins, suggesting a mechanism contributing to male pattern baldness.
      Cell Cycle Regulation and Regeneration

      research Cell Cycle Regulation and Regeneration

      27 citations , January 2012 in “Current Topics in Microbiology and Immunology”
      This study found similarities in the regeneration processes of MRL mouse ears and axolotl limbs, involving G2 cell cycle arrest and nerve-dependent mitosis, but the role of p21 in axolotl limb regeneration remains uncertain.
      Hormonal Therapies for Acne

      research Hormonal therapies for acne

      26 citations , October 2016 in “Clinics in Dermatology”
      This article discusses various hormonal therapies for acne and provides practical treatment guidelines for managing hormonally related acne, but it reports no new research findings.
      Pregnancy and Skin: Changes and Dermatoses

      research Pregnancy and Skin

      26 citations , June 2012 in “The Journal of Obstetrics and Gynecology of India”
      This review discusses various skin changes during pregnancy, noting that while most are benign and resolve after childbirth, some may require careful medical management for the safety of the mother and fetus; it reports no new results.
      Cutaneous Metabolism of Vitamin B-6

      research Cutaneous Metabolism of Vitamin B-6

      26 citations , February 2003 in “˜The œjournal of investigative dermatology/Journal of investigative dermatology”
      This study found that cutaneous pyridoxal 5'-phosphate hydrolase activity may be carried out by an enzyme different from the classical tissue-nonspecific alkaline phosphatase in human and mouse skin.
      Stem Cells and Aberrant Signaling of Molecular Systems in Skin Aging

      research Stem cells and aberrant signaling of molecular systems in skin aging

      25 citations , November 2014 in “Ageing Research Reviews”
      This review discusses the mechanisms of skin aging, highlighting the roles of stem/progenitor cells, genetic and environmental factors, and suggests potential for cell-based therapies, but reports no new experimental findings.
      Hair Growth Promotion Activity and Its Mechanism of Polygonum Multiflorum

      research Hair Growth Promotion Activity and Its Mechanism ofPolygonum multiflorum

      24 citations , January 2015 in “Evidence-based Complementary and Alternative Medicine”
      In this study, Polygonum multiflorum Radix promoted hair growth in mice, with oral administration being more effective, likely through FGF-7, while topical application favored SHH-related mechanisms.
      Hormone Therapy in Acne

      research Hormone therapy in acne

      24 citations , January 2013 in “Indian Journal of Dermatology, Venereology and Leprology”
      This review examines hormonal influences on acne development and available hormonal therapies but reports no new clinical results.
      Physiological Changes and Dermatoses of Pregnancy

      research Physiologic changes and dermatoses of pregnancy

      24 citations , June 2011 in “International Journal of Dermatology”
      This review summarizes physiologic skin changes during pregnancy and specific pregnancy-related dermatoses but reports no new clinical results.
      Hormones and Hair Growth

      research Hormone und Haarwachstum

      24 citations , May 2010 in “Hautarzt”
      This review explores various hormone influences on hair growth and loss beyond androgens, noting that clinical hormone therapies for aging may impact hair due to associated hormone level reductions, but reports no new empirical results.
      Immunology of Alopecia Areata

      research Immunology of alopecia areata

      23 citations , November 2020 in “Central-European Journal of Immunology/Central European Journal of Immunology”
      This review explores the autoimmune hypothesis of alopecia areata and the possible genetic and melanogenesis-associated autoantigens, but reports no new clinical findings.
      Critical Role of ATP-P2X7 Axis in UV-Induced Melanogenesis

      research Critical Role of ATP-P2X7 Axis in UV-Induced Melanogenesis

      23 citations , March 2019 in “˜The œjournal of investigative dermatology/Journal of investigative dermatology”
      This study found that extracellular ATP released from UVB-irradiated keratinocytes promotes melanin production through the P2X7 receptor, indicating a role for ATP-P2X7 signaling in UV-induced melanogenesis.
      Cutaneous Side-Effects of Beta-Adrenergic Blockers

      research CUTANEOUS SIDE-EFFECTS OF BETA-ADRENERGIC BLOCKERS

      22 citations , April 1985 in “Australasian Journal of Dermatology”
      This review discusses the uncommon but potentially serious cutaneous reactions to beta-adrenergic blockers and the uncertain pathogenesis, with no new clinical results reported.
      Fabrication of Polyvinyl Pyrrolidone-K90/Eudragit RL100-Based Dissolving Microneedle Patches Loaded with Alpha-Arbutin and Resveratrol for Skin Depigmentation

      research Fabrication of polyvinyl pyrrolidone-K90/Eudragit RL100-based dissolving microneedle patches loaded with alpha-arbutin and resveratrol for skin depigmentation

      21 citations , January 2023 in “Biomaterials Science”
      This study investigated the use of dissolving microneedle patches to improve the skin-lightening effects of alpha-arbutin and resveratrol, finding that the patches enhanced intradermal delivery and slightly decreased the melanin index without affecting skin hydration or causing irritation over 24 hours.