research Long-Term Treatment of Severe Hypertension with Minoxidil, Propranolol, and Furosemide
Minoxidil, propranolol, and furosemide effectively control severe hypertension, but may cause sodium retention.
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research Repurposing Existing Drugs for COVID-19: An Endocrinology Perspective
Existing drug dexamethasone may lower death risk in severe COVID-19 cases; more research needed for other drugs.
research Pharmacological Inhibition of Stearoyl CoA Desaturase in the Skin Induces Atrophy of the Sebaceous Glands
Blocking SCD1 in the skin with XEN103 shrinks sebaceous glands in mice.
research Thyroid Diseases and Skin Autoimmunity
Thyroid diseases may contribute to autoimmune skin diseases, and more research is needed on their relationship.
research Sexuality and Old Age
Older adults still engage in sexual activities but face challenges like health issues and lack of professional support, highlighting the need for better healthcare provider education and research on sexual fulfillment in old age.
research Estrogen Receptor Antagonist and Hair Regrowth in Dogs with Hair Cycle Arrest (Alopecia X)
Fulvestrant at 10 mg/kg does not promote hair regrowth in dogs with alopecia X.
research Treatment of Androgen Excess in Females: Yesterday, Today, and Tomorrow
The document concludes that treating androgen excess needs patience, managing expectations is important, and many drugs used are not officially approved, suggesting cosmetic options for mild cases.
research Macular Abnormalities Associated With 5α-Reductase Inhibitor
Using 5-alpha-reductase inhibitors, drugs for prostate issues and hair loss, may lead to eye abnormalities in men.
research Progenitor-Derived Endothelin Controls Dermal Sheath Contraction for Hair Follicle Regression
A specific signal from hair cells controls the tightening of the surrounding muscle, which is necessary for hair shedding.
research Scalp Cooling in the Prevention of Anthracycline-Induced Alopecia
Scalp cooling prevented hair loss in half of the patients, despite significant side effects.
research The Effect of Topical Minoxidil Pretreatment on Nonsurgical Delay of Rat Cutaneous Flaps: Further Studies
Minoxidil improved rat skin flap survival but was less effective than surgical methods.
research Phytotherapy in Benign Prostatic Hyperplasia
Serenoa repens is a common and effective plant-based treatment for mild-to-moderate prostate enlargement symptoms.
research Hirsutism Following the Use of Bimatoprost Eyedrops for Glaucoma
A woman got unwanted hair growth on her face from using bimatoprost eyedrops for glaucoma.
research Manifestation of Pityriasis Amiantacea Following Initiation of Minoxidil
A woman developed a rare scalp condition after starting minoxidil, which was resolved with specific shampoo and solution.
research Telogen Effluvium Need Not Recur
Hair loss from telogen effluvium may not happen again after another surgery.
research Enzymes
Enzymes are classified into six types and are essential for many biological processes, with only a few targeted by drugs.
research Human Fibroblast-Derived Matrix Hydrogel Accelerates Regenerative Wound Remodeling Through Interactions With Macrophages
A new hydrogel made from human cells improves wound healing by working with immune cells to promote repair.
research British Society for Pediatric Dermatology Annual Meeting, Sheffield, 18-19 November 2016
The meeting highlighted the importance of genetic testing and multidisciplinary approaches in pediatric dermatology.
research Comments Concerning the Real Risk of Sexual Adverse Events Secondary to the Use of 5-Alpha-Reductase Inhibitors
The document concludes that the risk of sexual side effects from 5-alpha-reductase inhibitors is low and often temporary, but more research is needed on potential permanent effects.
research DNA Dioxygenases Tet1/2/3 Control Hair Matrix Keratinocyte Differentiation and Hair Shaft Shape via Regulation of Hair Keratin Gene Expression
The enzymes Tet1, Tet2, and Tet3 are important for the development of hair follicles and determining hair shape by controlling hair keratin genes.
research Alopecia
The document concludes that alopecia has various forms, each with specific treatments, but no definitive cure for certain types like CCCA has been proven.
research Effect of 5α-Reductase Inhibitors on Sexual Function: New Contributions
5-alpha reductase inhibitors increase the risk of sexual dysfunction in patients treating enlarged prostate but not in those treating hair loss.
research Use of Spironolactone in Combination with an Oral Contraceptive in Treatment of Hirsutism
Spironolactone with an oral contraceptive improved hair growth in women with hirsutism.
research Finasteride Monotherapy Before TURP: Significant Improvement in Early Postoperative Quality of Life
Finasteride before TURP reduces blood loss and improves early postoperative quality of life.
research National Lipid Association Recommendations for Patient-Centered Management of Dyslipidemia: Part 2
The guidelines suggest lifestyle changes, diet adjustments, and personalized medication to manage dyslipidemia and reduce heart disease risk.
research Androgens and Hair Growth
Androgens can both increase and decrease hair growth in different parts of the body.
research Androgenetic Alopecia: Pathogenesis and Potential for Therapy
Hair loss needs more research for better treatments.
research Androgens and Human Hair Growth
Androgens can cause hair growth in some areas and hair loss on the scalp.
research Overview of Common, Rare, and Atypical Manifestations of Cutaneous Lupus Erythematosus and Histopathological Correlates
The document concludes that recognizing and treating cutaneous lupus erythematosus early is crucial for managing the skin and potential systemic symptoms.
research Testosterone, Dihydrotestosterone, and Incident Cardiovascular Disease and Mortality in the Cardiovascular Health Study
DHT may increase the risk of heart disease and death in elderly men.