29 citations
,
September 2019 in “Stem Cells International” This study observed that a treatment combining platelet-rich fibrin and micrograft spray-on skin led to rapid and complete wound healing in both massive and chronic burn patients within an average of 7-10 days.
29 citations
,
March 2017 in “International Journal of Women's Dermatology” This review found that combined oral contraceptives and spironolactone are effective treatments for adult acne in women, but noted that oral contraceptives increase the risk of venous thromboembolism and require individual risk assessment before use.
27 citations
,
January 2015 in “International Journal of Trichology” This study found that a marine-extract dietary supplement significantly reduced hair shedding and increased hair diameter in premenopausal women with subclinical hair thinning or hair loss after 6 months of use.
27 citations
,
December 2005 in “Journal of Cosmetic Dermatology” This study found that topical application of niacin derivatives significantly increased hair fullness in women with female pattern hair loss compared to a placebo after six months.
25 citations
,
August 2016 in “Journal of Cosmetic Dermatology” This study found that a marine complex supplement significantly reduced hair shedding and increased hair growth in men with thinning hair over 180 days.
25 citations
,
August 2014 in “Endocrinology” This study created a humanized mouse model of hereditary vitamin D-resistant rickets that lacks alopecia, indicating the mutant receptor's potential to explore the syndrome's characteristics beyond vitamin D binding.
24 citations
,
May 2018 in “Journal of Molecular Endocrinology” This article discusses the discovery of the first known menstruating rodent, the spiny mouse, and proposes that a significant increase in progesterone during the luteal phase is a unique feature of menstruating species, but reports no new experimental results.
24 citations
,
May 2010 in “Veterinary dermatology” This study found that both ciclosporin A and topical therapy were effective in reducing alopecia and scaling in dogs with idiopathic sebaceous adenitis, with evidence suggesting improved outcomes when both treatments are combined.
21 citations
,
September 2011 in “Journal of Pharmaceutical Sciences” This study found that the desolvation of finasteride hydrate solvates is highly dependent on the physical environment, complicating investigations but providing insight through complementary analysis techniques.
18 citations
,
November 2016 in “International clinical psychopharmacology” This study found that in a 10-week trial, inositol did not significantly reduce trichotillomania symptoms compared to placebo, although 42.1% of inositol-treated patients felt 'much or very much improved' at the study's end.
18 citations
,
July 1975 in “Clinical Pharmacology & Therapeutics” Oral minoxidil effectively controls blood pressure quickly and safely.
17 citations
,
January 1993 in “Journal of Gastroenterology and Hepatology” This study found that recombinant IFN α-2b injections in patients with acute post-transfusion hepatitis C can suppress viral RNA and lead to normalization of serum ALT, though long-term prevention of chronicity remains unclear.
13 citations
,
October 2010 in “Seizure” This study reported that extended-release valproate significantly reduced seizure frequency and improved quality of life in epilepsy patients over six months, despite some adverse effects like weight gain and tremor.
12 citations
,
July 2017 in “Scientific reports” In this study, researchers developed a simple, non-invasive method to monitor circadian gene expression using whole hair root cultures, finding that elderly dementia patients' peripheral clocks still oscillate similarly to younger, healthier individuals, which suggests cellular senescence minimally affects some aspects of circadian rhythms.
12 citations
,
September 2015 in “Drug Design Development and Therapy” This study found that the DOX derivative AD198 more effectively inhibited cell viability and induced apoptosis in canine cancer cell lines K9TCC and K9OSA compared to DOX in vitro.
12 citations
,
January 1998 in “Drug safety” Finasteride helps reduce prostate size and symptoms in BPH but is less effective than terazosin and works best for larger prostates.
11 citations
,
December 2017 in “Orphanet Journal of Rare Diseases” This study found a previously unreported ST14 gene mutation in a patient with ichthyosis-hypotrichosis syndrome, highlighting novel skin and hair characteristics and emphasizing the critical role of the Asp482 amino acid in matriptase activation.
9 citations
,
July 2017 in “Case Reports in Dermatology” This case study describes a 19-year-old female with hidradenitis suppurativa whose symptoms and metabolic abnormalities improved significantly over 3 years on a combined regimen, though some skin lesions persisted.
8 citations
,
August 2020 in “PLOS Computational Biology” This study presents a computational approach, CATNIP, which repurposes drugs using only their biological and chemical information, predicting new uses like adrenergic uptake inhibitors for Parkinson's and vandetanib for Type 2 Diabetes.
8 citations
,
January 2019 in “JAAD Case Reports” This article describes erosive pustular dermatosis of the scalp, emphasizing its chronic nature, potential complications, and the lack of specific diagnostic findings, but reports no new clinical results.
6 citations
,
June 2024 in “Biofabrication” This study used digital-light-processing bioprinting to create a 3D skin-on-a-chip model with a miniaturized vascular network to closely study immune cell interactions similar to real human skin, demonstrating the potential to analyze immune-T cell trafficking influenced by skin signals.
6 citations
,
April 2010 in “The American Journal of Surgical Pathology” This report highlights two cases where trichoblastoma in the breast was initially misdiagnosed as malignancy due to diagnostic challenges in needle core biopsies, emphasizing the importance of expert dermatopathologic review.
5 citations
,
May 2021 in “BMC surgery” This report of a rare case describes cutis verticis gyrate secondary to cerebriform intradermal nevus, emphasizing individualized treatment plans based on patient preference and condition severity.
5 citations
,
July 2019 in “Clinical and experimental dermatology” This study found that incorporating collagenase type I into a noncultured hair follicle cell suspension technique improved cell yield and enhanced repigmentation in patients with stable vitiligo compared to dermabrasion alone.
5 citations
,
October 2014 in “Journal of cosmetic and laser therapy” In this study, the researchers found that combining physical dermabrasion with chemical peeling increased growth factors and neuropeptides more than chemical peeling alone in porcine skin samples.
5 citations
,
June 2012 in “Journal of Cosmetic and Laser Therapy” This study found that combining topical finasteride with IPL + RF hair removal significantly reduced unwanted facial hair in women after six months compared to placebo.
4 citations
,
July 2024 in “Pharmacology Research & Perspectives” In this phase 2a study of adults with alopecia areata, researchers observed that ritlecitinib treatment did not result in significant differences in brainstem auditory evoked potential changes or axonal swelling compared to placebo, suggesting the dog toxicity findings may not be clinically relevant in humans.
4 citations
,
August 2021 in “The Malaysian journal of medical sciences/The Malaysian Journal of Medical Science” This review discusses the impact of calorie restriction on enhancing stem cell potency and regenerative abilities in mammalian tissues and reports no new experimental results.
4 citations
,
May 2021 in “Molecules” This study suggests that analyzing hair samples with a liquid chromatography-mass spectrometric assay may offer a reliable method to measure average quarterly vitamin D levels, potentially complementing blood tests.
4 citations
,
April 2017 in “International journal of reproduction, contraception, obstetrics and gynecology” This study found a 21-fold increased risk of metabolic syndrome associated with a higher waist-hip ratio in women with polycystic ovary syndrome, highlighting the need for focused management in obese patients.