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Certain changes to the B-ring of androgen receptor ligands can increase their effectiveness for potential treatments of muscle and bone conditions.

The document concludes that cosmetics need biocompatible, eco-friendly ingredients due to aging populations and demand for effective products.

Mice without the vitamin D receptor have bone issues and other health problems, suggesting vitamin D is important for preventing various diseases in humans.

Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.

Hair's strength and flexibility come from its protein structure and molecular interactions.

Researchers extracted tiny keratin filaments from human hair by unzipping its outer layer.

Mutations in the androgen receptor gene cause Androgen Insensitivity Syndrome, affecting sexual development.

Ethyl Carbitol is the best at preventing split ends in permed hair.

Abnormal cuticle and hair shaft medulla cause hair loss in androgenetic alopecia; sonography helps diagnose and manage it.

UVB radiation changes the chemical makeup and dries out human hair but doesn't alter its appearance or texture.

Hair and wool strength is affected by the number and type of bonds in their protein structures, with hair having more protein aggregates than wool.

Human skin responds to light with protective mechanisms, but more research is needed to understand these processes and their implications for health and therapy.

L-PGDS has specific binding sites for its functions and could help in drug delivery system design.

Electrostatic interactions mainly stabilize the binding of peptides to hair keratin.

Hair stiffness is higher when it has more para-like cortical cells.

Histone modification is key in treating chronic inflammatory skin diseases.

Understanding how androgens and their receptors work can lead to improved treatments for skin diseases.

The model shows that filament flexibility and amino acid differences affect how fast intermediate filament proteins assemble.

A new mRNA variant of the SCF gene in sheep skin produces a shorter, different protein.

A new mutation in the CYP11B1 gene was found in a woman with mild hyperandrogenemia, a rare cause of non-classic congenital adrenal hyperplasia.

Neurotoxins can affect neurotransmitter release and have potential in treating muscle, pain, and cancer conditions, but more research is needed on how they work.

Hair and nail cells share similar proteins, indicating a common differentiation pathway.

Selective Androgen Receptor Modulators (SARMs) are drugs that can control the effects of androgens in different tissues, potentially having fewer side effects and promising for treating various conditions.

Vitamin D receptor binds similarly to natural and synthetic ligands, affecting gene regulation.

ATG effectively reduces hair frizz without damaging hair strength.

Celsr1 is crucial for skin cell alignment, while Celsr2 has little effect on this process.

Biopolymers are increasingly used in cosmetics for their non-toxicity and skin benefits, with future biotech advancements likely to expand their applications.

The research gives new understanding on how human steroid 5α-reductases work and how drugs like finasteride inhibit them, which could help in creating new drugs.

A new gene mutation linked to a skin condition was found in a Spanish family.

A gene in Sebekia benihana, CYP-sb21, is needed for a specific reaction on the drug Cyclosporine A, which could be important for hair growth without affecting the immune system.