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The document explains different hair and scalp conditions, including common hair loss after pregnancy or illness, drug-induced hair loss, hereditary excessive hair growth, patterned baldness, autoimmune hair loss, and permanent loss due to skin disease, with generally limited treatment options.

Antiandrogens and androgen inhibitors like spironolactone, finasteride, and dutasteride can treat hair loss and skin conditions, but they have risks and side effects, including potential harm to pregnant women and risks of cancer and heart issues. Herbal remedies also have antiandrogenic effects but lack safety validation.

The best mix for a hair loss treatment cream is 10% Sophora japonica tincture and 5% Serenoa repens extract.

Hirsutism treatment should focus more on patient needs and quality of life.

Flutamide caused damage to male rat reproductive organs and may affect fertility.

Aldactone effectively reduces hair thickness in women with excessive hair growth, both alone and with other treatments.

Spironolactone effectively makes hair shafts thinner in women with excessive hair growth.

Eflornithine's effectiveness for women with facial hirsutism is unclear.

Spironolactone with an oral contraceptive improved hair growth in women with hirsutism.

Flutamide worked better than finasteride for reducing excessive hair growth in women, but had more side effects.

A new compound with strong antiandrogenic effects was found, potentially useful for treating conditions like acne and prostate cancer.

Different substances affect hair and skin cell growth in various ways.

Different substances affect hair and skin cell growth in various ways, with some promoting and others inhibiting cell proliferation.

Cyclosporin A and FK506 can start new hair growth in mice, but ascomycin and rapamycin cannot.

Spironolactone helped reduce excessive facial hair in a woman with porphyria cutanea tarda.

New treatments improve hair loss solutions for different age groups and genders.

Minoxidil helps with hair regrowth in women with androgenic alopecia.

The guidelines recommend informed consent for gender-affirming treatments and stress the importance of personalized, culturally sensitive care for transgender individuals.

Experts agree that PCOS affects women's health in complex ways, but more research is needed to understand and treat it effectively.

The guideline suggests using specific criteria to diagnose PCOS, recommends various treatments for its symptoms, and advises screening for related health issues.

PCOS is a complex condition with major health impacts, needing more research for better diagnosis and treatment.

Most women with excess male hormones have Polycystic Ovary Syndrome, and hormonal therapy can improve symptoms but may cause side effects.

Polycystic ovary syndrome is a complex condition that affects women's mental, reproductive, and metabolic health throughout their lives.

Polycystic Ovary Syndrome (PCOS) is a common condition in women that can cause metabolic, reproductive, and psychological issues, and requires lifestyle changes and medication for management.

The guideline recommends mental health involvement in diagnosing gender identity disorder and outlines hormone and surgical treatment protocols, emphasizing safety, informed consent, and long-term monitoring.

Women with PCOS should be screened for heart disease risk and manage their health to prevent it.

Male hormones may play a role in the development of heart disease, and more research is needed to understand their effects.

The document concludes that non-binary individuals need compassionate support and recognition in healthcare, without being pathologized.

The European Society of Endocrinology advises individualized long-term management for PCOS, focusing on lifestyle changes, accurate diagnosis, and treatments for associated health risks and symptoms.

Experts recommend using evidence-based methods to diagnose and treat hirsutism, focusing on symptoms and underlying causes.