The Impact of COVID-19 on the Menstrual Cycle: A General Perspective

    March 2023 in “ Brazilian Journal of Health Review ”
    Anna Caroline Loyola Sampaio, Jéssica dos Santos Coelho, Paloma Luna Maranhão Conrado, Valda Lúcia Moreira Luna, Pauliana Valeria Machado Galvão, George Alessandro Maranhão Conrado
    TLDR The combination tablet of finasteride and doxazosin works the same as taking each drug separately.
    The study aimed to evaluate the pharmacokinetic profile and bioequivalence of a fixed combination tablet containing finasteride (5 mg) and doxazosin (2 mg) compared to the individual administration of these drugs. Conducted as a randomized, crossover study with 30 subjects, the results showed no significant differences in the pharmacokinetic parameters (AUC0-72h, AUC0-∞, and Cmax) between the combination tablet and the single agents. The mean ratios of AUC0-72h/AUC0-∞ for finasteride and doxazosin were nearly 100%, indicating adequate sampling time and confirming bioequivalence. This suggests that the combination tablet does not alter the pharmacokinetics of the individual drugs, supporting its use in clinical practice.
    Discuss this study in the Community →

    Related Community Posts Join

    6 / 1000+ results

      community Huberman tweet about finasteride

      in Finasteride/Dutasteride  278 upvotes 1 year ago
      The conversation is about the side effects of finasteride, including Post Finasteride Syndrome, with varied personal experiences and differing views on the credibility of information sources. Some participants also discuss using minoxidil as a hair loss treatment.

      community Warning: Minoxidil usage around pets

      in Minoxidil  454 upvotes 7 months ago
      Minoxidil is highly toxic to pets, especially cats and dogs, even in small amounts. Many users have switched to oral minoxidil to prevent accidental exposure to their pets.

      community Where to get finasteride with no insurance?

      in Finasteride  31 upvotes 3 days ago
      Finasteride can be purchased at competitive prices from Costco, Amazon, and Cost Plus Drugs, with GoodRx offering local deals. Splitting 5mg tablets may reduce costs if approved by a doctor.

      community Is Topical Finasteride Safe for Cats in My Home?

      in Finasteride  46 upvotes 1 week ago
      Topical finasteride is not known to be toxic to cats like minoxidil, but careful handling is advised to prevent ingestion or skin contact. OP seeks reassurance to convince their girlfriend of its safety around their cat.

    Similar Research

    6 / 1000+ results