The Impact of COVID-19 on the Menstrual Cycle: A General Perspective

    March 2023 in “ Brazilian Journal of Health Review ”
    Anna Caroline Loyola Sampaio, Jéssica dos Santos Coelho, Paloma Luna Maranhão Conrado, Valda Lúcia Moreira Luna, Pauliana Valeria Machado Galvão, George Alessandro Maranhão Conrado
    TLDR The combination tablet of finasteride and doxazosin works the same as taking each drug separately.
    The study aimed to evaluate the pharmacokinetic profile and bioequivalence of a fixed combination tablet containing finasteride (5 mg) and doxazosin (2 mg) compared to the individual administration of these drugs. Conducted as a randomized, crossover study with 30 subjects, the results showed no significant differences in the pharmacokinetic parameters (AUC0-72h, AUC0-∞, and Cmax) between the combination tablet and the single agents. The mean ratios of AUC0-72h/AUC0-∞ for finasteride and doxazosin were nearly 100%, indicating adequate sampling time and confirming bioequivalence. This suggests that the combination tablet does not alter the pharmacokinetics of the individual drugs, supporting its use in clinical practice.
    Discuss this study in the Community →

    Related Community Posts Join

    6 / 1000+ results

      community Huberman tweet about finasteride

      in Finasteride/Dutasteride  278 upvotes 1 year ago
      The conversation is about the side effects of finasteride, including Post Finasteride Syndrome, with varied personal experiences and differing views on the credibility of information sources. Some participants also discuss using minoxidil as a hair loss treatment.

      community Warning: Minoxidil usage around pets

      in Minoxidil  454 upvotes 8 months ago
      Minoxidil is highly toxic to pets, especially cats and dogs, even in small amounts. Many users have switched to oral minoxidil to prevent accidental exposure to their pets.

      community Topical Finasteride Gel 1% after 4 months — problems

      in Finasteride  156 upvotes 3 days ago
      The user experienced hair thinning due to a testosterone spike and used a minoxidil solution and topical finasteride gel. After four months, the gel caused side effects without improving hair thinning, leading to questions about continuing or adjusting the treatment.

      community Finasteride not working (18M)

      in Finasteride  45 upvotes 5 days ago
      An 18-year-old is concerned that finasteride hasn't stopped his hair loss after several months. Suggestions include giving it more time, combining it with minoxidil, and consulting a dermatologist.

    Similar Research

    6 / 1000+ results