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BRL 7660, once studied for male contraception, showed promise as an acne treatment but was not developed further due to competing drugs.

Washing can prevent cancer from lubricating oils, extreme body temperatures need more study, Sulfomid is not recognized, no reliable diphtheria carrier treatment except surgery, eyelid injuries should heal before repair, heterophile antibody test is specific for mononucleosis, chlorine inhalations for colds are outdated, and wheat germ is safe.

The 2003 consensus updated PCOS diagnosis criteria and highlighted increased risks of diabetes and heart disease for those affected.

The 2003 consensus updated PCOS diagnosis criteria and linked PCOS to higher risks of diabetes and heart problems, recommending lifestyle changes to lower these risks.

Mice without the vitamin D receptor have bone issues and other health problems, suggesting vitamin D is important for preventing various diseases in humans.

Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

Human skin can make serotonin and melatonin.

Blocking the enzyme 5α-reductase can shrink the prostate and help treat enlarged prostate issues.

Chitin and chitosan are useful in cosmetics for oral care, haircare, and skincare, including UV protection and strength improvement.

Melatonin is important for skin health and protection, and can be made by the skin or applied to it.

Calcium affects where root hairs grow, but other unknown factors determine their growth direction.

Oestrogens are key for bone growth during puberty in both boys and girls.

Epirubicin is as effective as doxorubicin for cancer treatment with less heart damage, but doesn't work on doxorubicin-resistant cancers.

Some people with pattern hair loss may also have scalp inflammation and scarring similar to lichen planopilaris.

Using CDK inhibitors on rats showed a reduction in chemotherapy-caused hair loss, but later experiments could not repeat these results.

Stem cell self-renewal is complex and needs more research for full understanding.

Lupus affects the body and skin, causing joint pain and skin issues that can be treated with steroids and antimalarial drugs.

The document concludes that adenosine receptor agonists have potential for treating various conditions, but only a few are approved due to challenges like side effects and the need for selective activation.

Modulating BMP activity changes the number, size, shape, and type of ectodermal organs.

Substances from Chinese medicines show promise for immune support and disease prevention, but the way they are processed affects their effectiveness.

Minoxidil effectively treats hair loss, but use cautiously and monitor side effects.

Laminin-511 is crucial for early hair growth and maintaining important hair development signals.

Cystatin M/E strongly inhibits cathepsin V and cathepsin L, important for skin formation.

New treatments for Alopecia Areata show promise but need to be more effective and affordable.

Antiandrogens affect androgen-dependent body functions and are used for various medical conditions, with some risks like fetus feminization, but new forms like 17α-propylmesterolone show promise for acne without systemic effects.

Minoxidil effectively treats severe hypertension but may cause side effects, so careful monitoring is needed.

The circadian clock is crucial for tissue renewal and regeneration, affecting stem cell functions and having implications for health and disease.

BMP2 and BMP7 have opposite roles in feather formation.

Minoxidil effectively controls blood pressure in severe cases, but has serious side effects and causes hair growth in women.

The genus Sophora has compounds with potential health benefits and could lead to new drugs, but more research is needed to understand their effects and safety.