July 2026 in “Mendeley Data” Higher doses of oral minoxidil can help hair growth but need careful monitoring for side effects.
July 2026 in “Mendeley Data” Higher doses of oral minoxidil can help hair growth but need careful monitoring for side effects.
July 2026 in “Mendeley Data” Higher doses of oral minoxidil can help hair growth but may have safety risks.
July 2026 in “Mendeley Data” Higher doses of oral minoxidil can help hair growth but may have safety risks.
This study observed that both intradermotherapy with 5% minoxidil and topical minoxidil application resulted in perceived improvements in hair density and thickness among patients with androgenetic alopecia, with no significant difference between the two groups.
August 2022 in “Journal of The American Academy of Dermatology” This study observed a slight reduction in blood pressure in normotensive patients after taking a 5-mg dose of oral minoxidil, particularly within the first two hours and more so in those with high baseline blood pressure.
2 citations
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March 2021 in “Journal of Cosmetic Dermatology” This pilot study found that among male androgenetic alopecia patients, 2.5 mg oral minoxidil with platelet-rich plasma led to higher patient satisfaction than 1.25 mg, though hair count improvements were not statistically significant.
January 2026 in “Dermatologica Sinica” In this study, oral minoxidil (1.25 mg and 2.5 mg) and topical 5% minoxidil significantly promoted hair regrowth in men with androgenetic alopecia over six months, showing comparable efficacy across both oral and topical treatments.
71 citations
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January 2004 in “Dermatology” This study found that oral finasteride was more effective than 5% topical minoxidil in treating mild to severe androgenetic alopecia in males, with both treatments deemed effective and safe over 12 months.
March 2026 in “Journal of Pakistan Association of Dermatologists” This study found that low-dose oral minoxidil was more effective than topical minoxidil in increasing hair density and patient satisfaction among men with androgenetic alopecia, with fewer local side effects and better compliance reported over six months.
October 2024 in “International Journal of Pharmaceutical Sciences Review and Research” This study reviewed existing literature on Androgenetic Alopecia treatments, finding that minoxidil promotes hair growth but can cause side effects due to its traditional formulations. Novel delivery systems like film-forming sprays may reduce these side effects and enhance efficacy.
January 2015 in “Our Dermatology Online” This study found that intralesional triamcinolone was the most effective treatment for achieving over 50% hair regrowth in alopecia areata patients, especially those with single patches.
January 2022 in “Clinical, Cosmetic and Investigational Dermatology” This study reports promising results for alopecia universalis treatment using a combination of systemic methotrexate and low-dose corticosteroids with topical minoxidil, though monitoring for side effects is necessary.
January 2015 in “Przegla̧d dermatologiczny” This study observed that excimer light therapy, intralesional triamcinolone, and topical 5% minoxidil all had differing levels of effectiveness in treating alopecia areata, with variable results noted among treatments.
July 2026 in “Research Square” July 2026 in “Mendeley Data” September 2025 in “Journal of the American Academy of Dermatology”
November 2023 in “Current Dermatology Reports” This review found that oral minoxidil, particularly in low doses, is effective and safe for treating various types of hair loss, including androgenic alopecia, and may offer advantages over other treatments, such as improved convenience and enhancement of male sexual function.
October 2015 in “Elsevier eBooks” Minoxidil is effective for hair growth and safe for long-term use.
34 citations
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July 2011 in “Journal of Dermatological Treatment” This study found that a combination of 5% hexane extract of Curcuma aeruginosa and 5% minoxidil slowed hair loss and increased hair growth in men with androgenetic alopecia.
22 citations
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February 2008 in “Journal of Neurochemistry” This study found that minoxidil prevents long-term serotonergic toxicity induced by MDMA in rats, primarily by opening mitochondrial KATP channels and involving Akt and MAP kinases in its neuroprotective mechanism.
3 citations
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January 2022 in “Pharmaceutics” This review examines new formulations for delivering 5-α-reductase inhibitors to improve targeted drug delivery in androgenetic alopecia, but reports no new clinical results.
September 2024 in “Health of Man” This study found that low-dose dutasteride is effective and safe for treating male androgenetic alopecia, showing significant improvement in hair growth and reduction in hair shedding in most patients.
January 2022 in “Cosmoderma” This study found that combining oral minoxidil with dutasteride increased hair thickness, density, and new growth in male pattern baldness patients with minimal side effects.
1 citations
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January 2015 in “Hair therapy & transplantation” This study found that dutasteride increased hair growth metrics significantly more than finasteride in Korean men with AGA, but a meta-analysis suggests no overall significant efficacy difference between the two drugs.
34 citations
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February 1993 in “Journal of steroid biochemistry and molecular biology/The Journal of steroid biochemistry and molecular biology” This study found that 4-MA is a potent inhibitor of testosterone 5α-reductase in human tissues, promising potential for treating androgen-dependent skin conditions like male pattern baldness.
7 citations
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January 2018 in “International Journal of Trichology” Taking 5 mg/day finasteride can cause side effects in women with hair loss, but these are usually mild and fade over time, making the treatment beneficial in the long run.
January 2020 in “Korean journal of ophthalmology/Korean Journal of Ophthalmology” This study found that minoxidil increases trabecular meshwork cell permeability, possibly via the downregulation of tight junction proteins and the generation of reactive oxygen species.
This study found that both oral minoxidil and topical 5% minoxidil were effective and safe for treating female pattern hair loss over 24 weeks, with oral administration not being inferior to topical treatment.
4 citations
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April 2020 in “Dermatology practical & conceptual” This study reported that among postmenopausal women with female pattern hair loss, treatment with topical finasteride 0.5% and minoxidil 2% was more effective at improving hair condition than treatment with topical 17α-estradiol 0.05% and minoxidil 2%, particularly notable at 12-18 months of follow-up.