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This study reports that a new DART-HRMS method can effectively analyze intact hair for drug use timelines, with cocaine detection aligning with forensic standards and identifying multiple drugs from high-resolution data.

This case report highlights an 11-year-old girl with dermatopathia pigmentosa reticularis, identifying associated Salzmann's nodular degeneration of the cornea and emphasizing the need for a multidisciplinary management approach.

This study found that Smad4 is crucial for satellite cell amplification during skeletal muscle regeneration, with aged cells exhibiting less Smad4 and reduced regenerative capability in mice.

This study found that the methanolic extract of Carduus adpressus exhibited strong antibacterial, antioxidant, and wound-healing activities, suggesting its potential use in developing wound-healing agents.

This case report describes a 54-year-old woman with familial dyskeratotic comedones who experienced slight improvement in her skin lesions after three months of treatment with topical retinoids and urea cream.

In this study, researchers identified two novel peptidylarginine deiminases from treated rat keratinocytes, both showing enzyme activity with PAD‐R11 reflecting a characteristic of epidermal enzymes.

Nelfb is essential for dermal fat development and survival.

This case study illustrated that a patient's severe autonomic neuropathy due to amyloidosis prevented the expected development of heart failure symptoms despite significant cardiac abnormalities.

This study determined that the human steroid 5α-reductase enzymes localize to the endoplasmic reticulum in HeLa cells, with protein tagging affecting expression and inducing protein aggregates for some isoforms.

This case report describes a patient's psychiatric and medical journey after a cardiac arrest, focusing on managing agitated behavior without medication, leading to significant improvement in cognitive function over a 5-week hospital stay.

This review discusses the role of RDH12 in vision, its structural and functional aspects, and related disease mechanisms, but reports no new clinical results; it aims to support therapy development for inherited retinal dystrophies.

In this study, researchers found that the efflux of calcium in root hairs of Arabidopsis thaliana, particularly through the ER-localized ACA2 and ACA7, is crucial for modulating cytoplasmic calcium signals and enabling proper root hair growth, with disruptions leading to impaired elongation.

This case study reports that a heterozygous missense GJA1 mutation, p.Gly138Ser, in a 2-year-old boy with oculodentodigital syndrome primarily resulted in syndactyly, fifth finger hypoplasia, and hypotrichosis, without neurological or craniofacial abnormalities.

This study generated a gene-edited cashmere goat with improved cashmere yield and fiber length by integrating VEGF at the FGF5 site, offering insights into hair growth mechanisms.

This study illustrates the severe neonatal clinical presentation of Netherton syndrome, which can be fatal despite intensive care, highlighting a specific homozygous mutation (c.1431-12G > A) associated with lethal cases.

In this study, reflectance confocal microscopy was used to diagnose periorificial dermatitis, revealing specific skin changes such as hair follicle dilatation, increased vascular density, and inflammation, which help distinguish it from similar conditions.

This review highlights recent progress in developing androgen receptor degraders, such as PROTACs, for treating castration-resistant prostate cancer, and notes that several have entered phase I or II clinical trials, showcasing potential to address drug resistance challenges.

This study successfully isolated LGR6+ epithelial stem cells from rats and demonstrated their multipotency, suggesting potential for fracture healing research.

This study found mutations in the P2RY5 gene that are linked to autosomal recessive woolly hair in Pakistani families, implicating it in hair texture determination.

The researchers reported that targeting glycoprotein 130's signaling site in animal models promoted tissue regeneration and reduced osteoarthritis progression through anti-inflammatory and protective effects.

In this study, researchers developed a new variant of the Mercedes flap with releasing incisions for reconstructing medium-sized scalp defects, demonstrating complete defect closure without complications in three patients following a single operation with excellent aesthetic outcomes.

The chemical peel improved the appearance of hand spots safely and effectively.

This study identified specific genetic markers related to wool quality in Rambouillet sheep, which may aid breeders in making informed selection and breeding decisions for improved fine wool production.

This report identifies a novel splice-site variant in the LAMB3 gene linked to junctional epidermolysis bullosa, emphasizing the need for gene sequencing in diagnosing the disease.

In this report, two adult patients with Tatton-Brown-Rahman syndrome exhibited new cardiac features, such as atrial fibrillation and ventricular and atrial dilatation, highlighting the importance of cardiovascular follow-up in adults with this condition.

In this study, researchers found that circERCC6, a circular RNA identified in cashmere goat hair follicles, helps activate secondary hair follicle stem cells, with its role dependent on specific m6A modifications that interact with miR-412-3p to regulate BNC2 expression.

This study evaluates the effectiveness and safety of 2-mg and 4-mg doses of baricitinib in patients with alopecia areata who have lost at least 50% of their scalp hair, comparing outcomes between those with early and late onset of the disease.

This study identifies two previously unreported pathogenic RIPK4 gene variants, suggesting a functional link with cell adhesion molecules in ectodermal dysplasias.

This commentary highlights that while platelet-rich plasma (PRP) is widely used in orthopaedic and cosmetic treatments, its effectiveness is questionable and varies with different compositions and applications.

This study introduced laser-assisted exosome delivery and observed early signs of clinical improvement in two patients, though causality cannot be inferred from these preliminary, uncontrolled cases.