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Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.

Many potential alopecia treatments need more testing to confirm they promote acceptable hair growth with minimal side effects.

Finasteride improves hair growth in men with androgenetic alopecia.

Higher sebum levels are linked to more severe male baldness.

Dihydrotestosterone affects hair growth by changing the Wnt/β-catenin pathway, with low levels helping and high levels hindering growth.

Cholesterol balance is important for hair health, and problems with it can lead to hair loss conditions.

Dutasteride effectively treats benign prostatic obstruction, improves urinary flow, reduces prostate size, and may prevent prostate cancer, but can cause sexual side effects.

5-alpha reductase inhibitors can cause sexual side effects like erectile dysfunction and reduced sexual desire, sometimes lasting after stopping the drug.

S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.

Dutasteride 0.5 mg works better than finasteride and placebo for increasing hair in men with hair loss.

New regenerative medicine-based therapies for hair loss look promising but need more clinical validation.

Dutasteride 0.5mg improves hair growth in 78% of people with hair loss, but may cause sexual problems in some.

Finasteride may cause slight depression and anxiety.

Ginseng and its compounds may help hair growth and prevent hair loss, but more human trials are needed to confirm this.

Telogen Effluvium is a hair loss condition where treatment involves identifying and managing its triggers.

The enzyme 5α-reductase type 1 is important for blood vessel development and fertility in the uterus.

Certain drugs change freshwater snail shells to a "banana" shape.

Testosterone therapy and surgeries like mastectomy improve transgender men's lives and mental health with low risks and high satisfaction.

MorrF improves hair growth better than minoxidil alone.

New hybrid compound found to effectively prevent hair loss.

Non-drug methods like diet, supplements, and aromatherapy can help manage hair loss and its emotional impact.

The document concludes that hair loss is influenced by genetics and other factors, and while treatments like finasteride can help, they have limitations and side effects.

Hair from balding and non-balding areas regrows similarly on mice.

Massaging the scalp with a cosmetic containing certain natural inhibitors can significantly regrow hair in men with pattern baldness.

Finasteride slowly binds to 5-alpha-reductase, affecting enzyme stability and inhibitor potency.

The composition with carnitine, thioctic acid, and saw palmetto extract may effectively reduce inflammation in hair follicle cells.

Inflammation may be linked to hair loss, and targeting specific enzymes could help treat it.

5α-Reductase inhibitors may increase depression risk but not dementia or suicide.

Saw palmetto in hair products might reduce hair loss but can cause side effects.

Genetic differences within ethnic groups may affect prostate cancer treatment effectiveness.