21 citations,
January 2003 in “Seminars in reproductive medicine” The document concludes that various drugs can manage symptoms and metabolic issues in women with PCOS.
15 citations,
October 2003 in “Dermatologic Surgery” Minoxidil, finasteride, and hair transplantation combined give best results for hair loss.
November 2003 in “Dermatologic Surgery” Minoxidil, finasteride, and hair transplantation combined give best results for hair loss.
21 citations,
January 2003 in “Skin pharmacology and physiology” Different skin cells process testosterone differently, and certain drugs can change this process, possibly helping treat acne and hair loss.
January 2006 in “The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology” Rubus coreanum may help hair growth but not through the tested mechanisms, and none of the herbal extracts help with acne.
49 citations,
April 2012 in “Phytotherapy Research” Rosemary leaf extract may be an effective natural treatment for hair growth and male pattern baldness.
16 citations,
September 2016 in “Neuropharmacology” Activating TSPO helps protect the retina from damage caused by high eye pressure in glaucoma.
14 citations,
December 1998 in “The Journal of Clinical Endocrinology and Metabolism” MENT could be a better option than testosterone for male hormone therapy and birth control because it works well at lower doses and has fewer side effects on the prostate.
10 citations,
January 2019 in “Journal of Chromatography B” Researchers developed a reliable way to measure hormones in urine, showing that a baldness treatment doesn't change hormone levels.
January 2003 in “Elsevier eBooks” Androgens and other hormones affect hair growth and skin conditions like acne.
3 citations,
November 2005 in “Women's health” Excessive body hair in women can be caused by various conditions and treated with medication like Diane® 35 or androgen blockers.
131 citations,
August 2004 in “Best Practice & Research in Clinical Obstetrics & Gynaecology” The conclusion is that PCOS is caused by ovarian sensitivity to hormones and disrupted hormone control, possibly due to ovarian factors, and more research is needed.
257 citations,
July 2018 in “Obstetrics & Gynecology” PCOS is a complex disorder in women that can lead to various health risks and requires personalized treatment.
70 citations,
March 2016 in “Urologic Clinics of North America” The document explains how the male reproductive system works, its role in making testosterone, and how conditions like obesity can disrupt it, leading to low testosterone and fertility issues.
403 citations,
November 2005 in “Journal of Endocrinology” Dehydroepiandrosterone (DHEA) is a prohormone important for producing sex steroids and has potential health benefits.
17 citations,
February 2015 in “Phytochemistry Reviews” Southeast Asian herbs show promise for skin and hair care, but more research is needed to confirm their effectiveness in cosmetics.
20 citations,
January 2016 in “Open Journal of Endocrine and Metabolic Diseases” PCOS affects fertility and is linked to obesity and menstrual irregularities; lifestyle changes are recommended for treatment.
3 citations,
October 2020 in “Bladder cancer” 5α-reductase inhibitors don't stop bladder cancer from developing or getting worse.
39 citations,
April 2007 in “Therapeutic Drug Monitoring” Finasteride affects urinary steroid profiles and can potentially hide steroid abuse in sports drug testing.
20 citations,
May 2018 in “The Journal of Urology” Men taking 5-alpha-reductase inhibitors before or after bladder cancer diagnosis had a lower risk of dying from the disease.
3 citations,
July 2021 in “Drug Testing and Analysis” 5α-reductase inhibitors can interfere with doping tests by masking banned substances.
72 citations,
April 2008 in “The Journal of urology/The journal of urology” Dutasteride and finasteride do not significantly affect bone density, blood fats, or blood production, but slightly lower PSA levels and minimally impact sexual function in healthy young men.
15 citations,
May 2007 in “Hormones and Behavior” Finasteride boosts morphine's pain relief, stops tolerance, and reduces withdrawal in rats.
75 citations,
November 1996 in “Fertility and Sterility” Finasteride effectively reduces hair growth in women with idiopathic hirsutism, but requires careful contraception during treatment.
28 citations,
February 1999 in “Archives of Dermatological Research” Finasteride potentially treats hair loss by reducing DHT production.
122 citations,
July 1990 in “Teratology” Finasteride exposure in pregnancy causes genital abnormalities in male rats.
86 citations,
March 1993 in “Toxicology and Applied Pharmacology” Finasteride affects male rat genitalia development, causing abnormalities during specific pregnancy days.
6 citations,
March 2015 in “Journal of Endocrinological Investigation” Taking both finasteride and dutasteride for prostate issues may raise the risk of heart problems.
22 citations,
November 2018 in “Breast Cancer Research and Treatment” The medications 5α-reductase inhibitors and spironolactone are generally safe for breast cancer patients on endocrine therapies and do not significantly increase breast cancer risk.
11 citations,
January 2017 in “Journal of Endocrinology/Journal of endocrinology” Female mice with disrupted 5α-reductase 1 had significant metabolic issues, including stress response problems, insulin resistance, liver fat buildup, and obesity.