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Licorice extract helps hair growth and may treat hair loss.

Gene mutations can cause problems in male genital development.

Creating stronger blockers for skin enzymes might lead to better treatment for conditions like acne and excessive hair growth.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Finasteride effectively treats BPH, but needs more trials to understand potential.

Sebocytes play a key role in controlling androgen levels in human skin.

Hormone treatments in transsexual individuals reduce hair growth and oil production in male-to-females and increase them in female-to-males.

Male hormones, particularly DHT, are linked to male pattern hair loss, and treatments like finasteride can help, but they don't work for postmenopausal women's hair loss, which may have different causes.

Too much androgen can cause hair loss; finasteride may help.

Certain genetic variations in the AR and ERβ genes can affect androgen levels in women.

Certain steroids in the brain affect mood and symptoms of depression, and treatments targeting these steroids show promise for improving these symptoms.

5α-reductase inhibitors can cause sexual problems, higher risk of aggressive prostate cancer, and depression.

Finasteride effectively treats hirsutism in women, but more research needed for long-term results.

High testosterone to epitestosterone ratio in hair could predict male-pattern baldness.

The enzyme that changes testosterone to a stronger form is mostly found in the part of the hair follicle called the dermal papilla.

Finasteride reduces alcohol withdrawal severity in male mice but increases it in female mice.

Certain 4-azasteroids are effective at blocking the enzyme that processes testosterone in human skin and could help treat acne, excessive hair growth, and male pattern baldness.

Finasteride effectively treats male hair loss, improving growth and density.

Hormonal therapy is a treatment option for acne, the only medical treatment for hirsutism, and the most promising for androgenetic alopecia.

Benign Prostatic Hyperplasia may be caused by changes in how the body processes male hormones.

Over 50% of women over 50 experience hair loss, with minoxidil being the only proven effective treatment.

Antiandrogen drugs can reduce PSA levels in women with excess hair, suggesting PSA is a sign of male hormone activity in women.

Blocking 5α-reductase can harm memory and brain structure, and increase harmful brain changes in male mice used for Alzheimer's disease research.

Men with male-pattern baldness have higher levels of certain testosterone metabolites and may have more active androgen metabolism.

Androgens, like DHT, affect hair growth and treatments like finasteride may help.

The enzyme 5α-reductase is important for proper blood vessel development during the fertility-related transformation of the uterus lining.

Finasteride can have lasting negative effects on brain function and behavior by disrupting neurosteroid production.

The document says that early treatment of Acne Vulgaris is important to prevent scarring and that adult onset acne is common in women, often due to hormonal imbalances.

Finasteride, a drug used for certain conditions, can cause serious side effects like sexual dysfunction, suicidal thoughts, and increased diabetes risk, and there's a need for more awareness and research about these effects.

The report concludes that PCOS is mainly a condition of excess male hormones and its definition may change as new information is discovered.