2 citations
,
July 2025 in “Forensic Sciences” This review concludes that anabolic–androgenic steroid abuse may lead to significant neurotoxicity, affecting brain structure, neurotransmitter systems, and increasing the risk of mood disorders and cognitive deficits.
1 citations
,
September 2025 in “Physiologia” This study found that systemic ovalbumin–aluminum sensitization followed by cutaneous challenge in mice induced thermal hyperalgesia, increased spinal cord gliosis, and sprouting of nociceptive fibers, along with elevated mast cell and nerve profile densities in the skin compared to controls.
5 citations
,
November 1992 in “Current problems in dermatology” This review discusses the role of glucocorticoids in treating severe inflammatory disorders and highlights their potential adverse effects, recommending dosage management to minimize these risks; no new clinical results are reported.
January 2009 in “Elsevier eBooks” This chapter reviews botanical treatments for polycystic ovary syndrome, discussing potential benefits but presenting no new clinical results; it emphasizes the use of botanicals for managing symptoms like anovulation, insulin resistance, and inflammation.
77 citations
,
July 2020 in “Journal of the European Academy of Dermatology and Venereology” This review examines the skin exposome, including solar exposure, air pollution, hormones, nutrition, and psychological factors, but reports no new clinical results.
24 citations
,
October 2017 in “Biomolecules” This review discusses the broader roles of angiogenic factors, like VEGFs and FGFs, beyond angiogenesis, highlighting their involvement in various biological and pathological processes.
4 citations
,
October 2013 in “Springer eBooks” This chapter reviews existing knowledge about melatonin's MT₁ and MT₂ receptors in human tissues, discussing their established and potential functions, but reports no new clinical findings.
222 citations
,
January 2005 in “Endocrine journal” This article discusses the potential role of melatonin in protecting skin against stress and maintaining homeostasis, based on its local synthesis and various protective functions, but presents no new clinical results.
220 citations
,
August 1988 in “Clinical endocrinology” This review provides a comprehensive overview of melatonin's physiological roles, effects, and clinical implications, but it does not present new experimental findings.
98 citations
,
July 2014 in “Trends in Molecular Medicine” This article discusses the role of human hair follicles in neuroendocrinology and suggests potential new therapeutic targets by examining how neuromediators influence hair growth, pigmentation, and stem cell biology in organ cultures.
83 citations
,
January 2001 in “American journal of clinical dermatology” This review discusses the clinical features of trichotillomania and the challenges in its diagnosis and treatment, reporting no new clinical findings while highlighting the need for specialized therapy and better therapeutic options.
81 citations
,
January 2011 in “European Journal of Internal Medicine” This review updates on the understanding and management of eating disorders, noting substantial progress over 30 years but highlighting the need for revised classification, clarified pathogenesis, and improved treatments.
28 citations
,
May 2015 in “Addiction Biology” This study found that early life stress significantly affects hedonic sensitivity to high-palatable food by altering gonadal hormones in prenatally-stressed male and female rats, with sex-dependent changes in reward-related behaviors and neurochemistry.
14 citations
,
January 2017 in “Elsevier eBooks” This review explores cannabigerol (CBG) as a potential therapeutic agent with various pharmacological activities but reports no new clinical results, emphasizing the need for further research on its efficacy and safety.
14 citations
,
October 2016 in “Psychoneuroendocrinology” This study identified significant changes in the expression of nine proteins in the nucleus accumbens of rats treated with finasteride, suggesting potential novel targets for its neuropsychiatric effects.
13 citations
,
November 2024 in “Frontiers in Microbiology” This review assessed the potential of mesenchymal stem cell therapy to enhance burn wound healing, highlighting its capabilities in promoting angiogenesis, reducing inflammation, and regenerating damaged tissues, while identifying preclinical and clinical challenges that need addressing to optimize treatment outcomes.
3 citations
,
September 2014 in “Journal of obstetrics and gynaecology Canada” Menopause often leads to lower sexual desire and discomfort during sex, but treatment should be personalized and only if it bothers the woman.
September 2025 in “Romanian Journal of Medical Practice” In this study of women with female pattern hair loss, iron deficiency was associated with the condition due to significantly lower serum ferritin and altered hematological indices compared to healthy controls, while no significant differences in serotonin levels or renal function were observed.
July 2024 in “International Journal of Pharmaceutical Sciences and Medicine” This review highlights that Nyctanthes arbor-tristis contains numerous phytochemicals and has traditional uses for various conditions. It also reports pharmacological activities, suggesting potential benefits for diabetes, cancer, inflammation, and more.
March 2022 in “Biomedical Journal of Scientific & Technical Research” This review discusses therapeutics for mitochondrial dysfunction and reports no new clinical findings.
January 2021 in “International Journal of Advanced Research in Medicine” This study observed that propranolol, flunarizine, and divalproex sodium were equally effective in managing migraine across a three-month period in a group of 84 patients, with various side effects noted among the drug groups.
506 citations
,
January 2012 in “Molecular and Cellular Endocrinology” This review details the expression and diverse functions of melatonin receptors in non-neural tissues and reports no new clinical findings, emphasizing their potential as therapeutic targets across various physiological and pathological processes.
349 citations
,
January 2005 in “The FASEB journal” This review discusses the cutaneous serotoninergic/melatoninergic system's potential role in skin function and resilience against environmental and internal stresses, but does not report new experimental findings.
67 citations
,
May 2018 in “Journal of Ginseng Research” This paper highlights the need for a comprehensive red ginseng monograph to provide standardized information on its components, certified functionality, efficacy, action mechanisms, and safety, especially given its widespread use as a health functional food in South Korea and interest in its benefits worldwide.
57 citations
,
May 2014 in “Molecular Phylogenetics and Evolution” This study utilized a sequence-structure alignment approach to improve the characterization of Class A Rhodopsin GPCR superfamily, including orphan and unclassified receptors, through evolutionary analysis.
50 citations
,
May 2019 in “Drugs” This review discusses the potential therapeutic effects of targeting the endocannabinoid system for chemotherapy-induced peripheral neuropathy and reports no new clinical results, highlighting the need for ongoing research.
48 citations
,
July 1996 in “Human & Experimental Toxicology” Human enzymes can detoxify harmful substances but might also increase their cancer risk.
39 citations
,
April 2020 in “IntechOpen eBooks” The authors describe drug repurposing as a promising strategy for finding new uses for existing drugs, noting it is efficient, cost-effective, and poses lower risks than traditional drug discovery processes, potentially aiding in the treatment of rare and difficult-to-treat diseases.
35 citations
,
December 1979 in “Naunyn-schmiedebergs Archives of Pharmacology” These drugs raise prostaglandin-like material in dog blood, possibly causing blood vessel widening.
23 citations
,
March 2010 in “Medical hypotheses” This review explores potential new roles for Merkel cells, including involvement in magnetoreception, fingerprint formation, and transmitting environmental information, but reports no experimental results.