The Role of Serotonin, Ferritin, and Hematological Profiles in Female Pattern Hair Loss
September 2025
in “
Romanian Journal of Medical Practice
”
Studysummary In this study of women with female pattern hair loss, iron deficiency was associated with the condition due to significantly lower serum ferritin and altered hematological indices compared to healthy controls, while no significant differences in serotonin levels or renal function were observed. Our plain-language summary of this paper — not a Tressless recommendation.
This study investigated the role of serotonin, ferritin, and hematological profiles in female pattern hair loss (FPHL) by comparing 65 FPHL patients with 65 healthy controls. The results showed that FPHL patients had significantly lower serum ferritin levels and reduced hematological indices, indicating subclinical iron deficiency, while no significant differences were found in serotonin levels or renal function markers. The findings suggest that iron deficiency is associated with FPHL, whereas serotonin and renal function do not significantly contribute. The study highlights the importance of assessing iron status in women with hair loss for clinical relevance and further research.