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A specific metabolite, not a receptor protein, triggers the production of certain kidney enzymes, but this process is disrupted in mice with a mutation causing testicular feminization.

Dihydrotestosterone (DHT) is crucial for conditions like male-pattern baldness and acne, and measuring a byproduct, androstanediol glucuronide, is a better way to assess DHT's effects than DHT blood levels.

Male pattern baldness is mainly caused by a hormone called dihydrotestosterone (DHT), and drugs that can block this hormone might help prevent hair loss.

Male hormones, particularly DHT, are linked to male pattern hair loss, and treatments like finasteride can help, but they don't work for postmenopausal women's hair loss, which may have different causes.

Androgens, like DHT, affect hair growth and treatments like finasteride may help.

Iron supplements may reverse premature graying in iron-deficient individuals; ingrown nails are common in diabetics with certain risk factors; topical finasteride may reduce scalp DHT as effectively as oral finasteride; monilethrix treatment is challenging but some medications can help.

Hormones and metabolism play a complex role in prostate enlargement, and more research is needed to improve diagnosis and treatment.

5α‐reductase isozymes are crucial for prostate development and health, and targeting them can help prevent and treat prostate issues.

Androstanediol glucuronide is a reliable marker for hirsutism in women.

The document concludes that more research is needed to understand excessive hair growth in women with normal hormone levels and regular ovulation.

Finasteride and CPA-EE2 equally reduce hirsutism, but affect hormone levels differently.

Dihydrotestosterone can be made from dehydroepiandrosterone in skin cells without needing testosterone.

Epitestosterone may act as a weak antiandrogen and can inhibit an enzyme involved in testosterone metabolism.

Testosterone and dihydrotestosterone play a role in women's health issues like excess hair and baldness, and treatments blocking these hormones may help.

Suppressing certain hormones might help prevent prostate cancer.

Androgens affect skin conditions like acne and hair loss through specific biochemical pathways.

The new progesterone derivatives effectively inhibit 5α-reductase and bind to the androgen receptor.

Finasteride shows promise for treating hair loss and excessive hair growth, but more research is needed to confirm its effectiveness and safety.

Some plant-based chemicals may help with hair growth, but more research is needed to confirm their effectiveness.

DHT inhibition may increase spinal bone growth in ankylosing spondylitis.

Acanthus ebracteatus Vahl. extract and verbascoside may help prevent hair loss and promote hair growth due to their anti-inflammatory properties and ability to protect against cell death.

Finasteride use may be linked to rare testicular tumor, but more research needed.

Finasteride, when taken daily, lowers dihydrotestosterone levels but doesn't noticeably affect adrenal steroid production, except by blocking the 5 alpha-reductase enzyme.

Italian guidelines recommend using trichoscopy for diagnosis and treatments like minoxidil for hair loss.

Hair loss in men is mainly caused by hormones and genes, and while current treatments can slow it down, they can't fully stop it.

Germacrene analogs, especially 8-Hydroxy germacrene B, are more effective than germacrone at blocking a hormone-related enzyme and could help treat hair loss.

Male pattern hair loss affects up to 80% of men due to genetics and hormone sensitivity.

Finasteride doesn't change polycystic ovary size or cyst number, suggesting testosterone's role in their appearance.

Finasteride reduces prostate size and serum levels, helping manage benign prostatic hyperplasia, without affecting prostate cancer detection. Regular monitoring is needed for users.

Early surgery reduces seizure risk in drug-resistant epilepsy; testosterone to DHT conversion doesn't affect muscle anabolism; veterans with PTSD likely to have riskier opioid use; bevacizumab helps in hereditary bleeding disorder.