Nonscarring Alopecias: Male Pattern Hair Loss

June 2015 in “ CRC Press eBooks ”

Colombina Vincenzi, Antonellá Tosti

male pattern hair loss MPHL dihydrotestosterone DHT androgen-sensitive hair follicles 5-alpha reductase enzymes male pattern baldness testosterone metabolite

TLDR Male pattern hair loss affects up to 80% of men due to genetics and hormone sensitivity.

Male pattern hair loss (MPHL) affected up to 80% of men over their lifetime and was characterized by a progressive reduction in hair diameter, length, and pigmentation, primarily in the frontal, temporal, and vertex areas of the scalp. This condition resulted from the effects of dihydrotestosterone (DHT), a testosterone metabolite, on androgen-sensitive hair follicles. The sensitivity to androgens was genetically determined and depended on DHT production through 5-alpha reductase enzymes.

View this study on taylorfrancis.com →

Discuss this study in the Community →

Related Community Posts Join

6 / 1000+ results

community Dutasteride SAVES your hair follicles: MAJOR BS on people who say it destroyed their hair permanently.

in Finasteride/Dutasteride 157 upvotes 11 months ago

The conversation discusses the effectiveness of hair loss treatments, specifically finasteride and dutasteride. The conclusion is that dutasteride significantly reduces DHT levels and may be more effective than finasteride for long-term hair retention, with some users reporting personal experiences and side effects.

community Better then Minoxidil( at least for me and my family)

in Treatment 42 upvotes 9 months ago

Capronium Chloride and Trichoxidil are suggested as better alternatives to Minoxidil for hair growth without heart side effects. The Japanese Dermatological Association recommends topical Minoxidil over Capronium Chloride.

community 57% increased chance of pattern hair loss independently associated with the consumption of sugary beverages in men (p<0.001) Pt 2

in Research/Science 480 upvotes 3 months ago

Sugary beverages increase the risk of pattern hair loss in men by 57%. Treatments discussed include Minoxidil, finasteride, and RU58841.

community I am a dermatologist with a clinical interest in alopecia. AMA

in Will treatment work for me? 2 years ago

In this conversation, 4990 discussed various treatments for hair loss, including oral minoxidil, PRP, transplan, Jak inhibitors, Dutasteride, Finasteride, Olumiant, Ketoconazole, RU58841, microneedling, baricitinib, and CCCA. They recommended scalp biopsies in unclear cases of DUPA, twice weekly to twice daily shampooing for topical minoxidil users, and two sessions spaced one month apart with follow up at month three to determine the effectiveness of PRP treatment.

community Anyone who is not taking fin after hair transplant, how is you hair now?

in Transplants 81 upvotes 1 year ago

The conversation is about the effectiveness of finasteride (fin) in preventing hair loss after a hair transplant. Some users have experienced hair thinning and loss after stopping finasteride, while others have had success with finasteride and minoxidil (min) in maintaining their transplanted hair. The general consensus is that finasteride is important for younger patients to prevent further hair loss.

community 12 mo 1 ml daily Min/Dermaroller 1mm-1.5mm update + AGA progression theory and specific order of treatment

in Microneedling 15 upvotes 3 years ago

A user shared their year-long hair loss treatment using minoxidil, microneedling, and scalp massages, reporting moderate hair growth and stabilization. They suggest starting early with less harmful methods and consider adding finasteride or dutasteride if needed.

Similar Research

5 / 1000+ results

research Hormonal Treatment for Skin Androgen-Related Disorders

January 2015

Hormonal treatments can help with hair loss, acne, and excess hair growth, but it takes 3-6 months to see results and patients should know the possible side effects.

research Guidelines for the Diagnosis and Treatment of Male-Pattern and Female-Pattern Hair Loss, 2017 Version

36 citations, June 2018 in “Journal of Dermatology”

Use finasteride, dutasteride, and minoxidil for hair loss treatment.

research Pattern Hair Loss in Men: Diagnosis, Genetic Link, Clinical Features, and Treatments

58 citations, September 2012 in “Dermatologic Clinics”

Male pattern hair loss caused by follicular miniaturization; early diagnosis and treatment can reduce psychological burden.

research A Scientific Hypothesis on the Role of Nutritional Supplements for Effective Management of Hair Loss and Promoting Hair Regrowth

3 citations, May 2018 in “Journal of nutritional health & food science”

Nutritional supplements can help manage hair loss and promote hair growth by strengthening hair roots and countering harmful effects of pollution, smoking, and deficiencies in vitamins and minerals.

research Androgenetic Alopecia in Men: An Update on Genetics

May 2024 in “Indian Journal of Dermatology”

Androgenetic alopecia in men is genetic and linked to health issues like obesity and heart disease, with treatments including minoxidil, finasteride, and hair transplants.