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Scientists made new substances that can block an enzyme linked to prostate issues and hair loss, with potential for creating a new treatment.

Androgens significantly affect female hair loss, and hormonal treatments may help.

The new compounds moderately block a specific enzyme and strongly counteract a male hormone, suggesting potential for treating certain male-related health conditions.

LY191704 is a compound that effectively blocks a specific enzyme involved in hormone conversion and could help treat enlarged prostate and hair loss.

Selective non-steroidal inhibitors of 5α-reductase type 1 can help treat DHT-related disorders.

Certain 4-azasteroids are effective at blocking the enzyme that processes testosterone in human skin and could help treat acne, excessive hair growth, and male pattern baldness.

New compounds may soon be tested to treat excessive hair growth in women.

New steroid compounds effectively inhibit 5α-reductase and may treat hair loss.

Four-amino acid part makes enzyme sensitive to finasteride.

Certain drugs that block specific enzymes can help treat prostate diseases.

Finasteride helps treat hair loss and prostate enlargement by blocking a specific enzyme.

Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

New treatments for enlarged prostate are being developed, some of which may be more effective than current medications.

Natural herbal compounds might treat certain medical conditions by reducing DHT levels, but more research is needed to confirm their effectiveness and safety.

5α-reductase inhibitors and alpha-1 adrenergic antagonists together effectively treat benign prostatic hyperplasia, with long-term benefits.

New research is needed to create better drugs that block the enzyme responsible for conditions like male baldness and prostate enlargement.

Low-dose finasteride effectively reduces hirsutism without serious side-effects.

FCE 28260 is a stronger and longer-lasting inhibitor of 5α-reductase than finasteride, which may make it a better treatment for certain medical conditions.

Testosterone conversion to 5α-DHT may not be essential for its effects on the skin.

The study created a new method to test drugs that affect hormone processing in skin.

Finasteride reduces male rat fertility by causing issues with copulatory plug formation.

Minoxidil boosts enzymes that help hair growth.

Finasteride temporarily lowers male rat fertility without affecting libido.

New chemical compounds were made that effectively block an enzyme linked to prostate growth.

The side gland of Suncus murinus is a good model for studying human sebaceous glands.

Inhibitors of the enzyme 5 alpha-reductase could potentially treat disorders like prostate cancer and baldness.

A new method was developed to make finasteride for treating hair loss.

The document concludes that targeting 5α-reductase, the androgen receptor, and hair growth genes, along with using compounds with anti-androgenic properties, could lead to more effective hair loss treatments.

Rat skin takes up and processes testosterone differently than other organs, with testosterone being more important for the skin than its metabolite 5α-DHT.

Finasteride safely lowers DHT levels without affecting testosterone.