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5-alpha-reductase inhibitors may help stabilize or slow down hair loss in some frontal fibrosing alopecia patients, but more research is needed to confirm their effectiveness and safety.

Taking 5-alpha reductase inhibitors does not increase breast cancer risk in men.

Using finasteride or dutasteride does not increase the risk of male breast cancer.

Store Tectona grandis leaf extracts in slightly acidic, light-protected conditions for best stability.

5-Alpha reductase inhibitors are safe long-term but may be outdated for preventing less significant prostate cancer.

4-(4-Phenoxybenzoyl)benzoic acid derivatives can both increase and decrease certain types of reactive oxygen species, and may be relevant to hair loss.

Finasteride slowly binds to 5-alpha-reductase, affecting enzyme stability and inhibitor potency.

Rats had lasting erectile problems after stopping a certain medication.

New pregnane derivatives are effective at inhibiting an enzyme linked to hair loss and reducing oil gland activity.

Researchers developed a new method to find substances in herbs that can block a specific enzyme linked to hair loss.

Certain Dibenzo derivatives may help treat prostate cancer.

New treatments for male pattern hair loss look promising, but established treatments are still the main option.

5α-reductase inhibitors may worsen sexual drive and spontaneous erections but don't worsen existing erectile or ejaculatory problems.

5α-reductase inhibitors may prevent prostate cancer but could also raise the risk of more severe cancers.

Women also use 5α-reductase inhibitors, and their effects differ from men.

Benzo[c]quinolizin-3-ones are effective nonsteroidal inhibitors of human steroid 5α-reductase 1.

Plant-based compounds might be effective, low-side-effect treatments for prostate cancer by blocking a specific enzyme.

Dutasteride use can lead to a stable decline in sexual function that is not affected by age or prostate size.

Lygodii Spora extract may help treat hair loss by blocking a hair loss-related enzyme and promoting hair growth.

No effective treatment for frontal fibrosing alopecia was found, but oral 5-alpha-reductase inhibitors had the best response; for lichen planopilaris, topical corticosteroids were commonly used but had a high relapse rate.

The study created a model to help design new inhibitors for steroidal 5α-reductase enzymes.

Best treatment for Frontal Fibrosing Alopecia is 5-alpha-reductase inhibitors and intralesional corticosteroids.

Spironolactone works well for acne and hirsutism, isotretinoin is very effective for acne and may have antiandrogenic effects, and 5 alpha-reductase inhibitors should be considered antiandrogens.

Compounds 4, 4b, and 4c effectively inhibit an enzyme linked to testosterone conversion without significant toxicity.

5α-reductase inhibitors may increase the risk of depression and suicidal thoughts.

Nanocarrier-based treatments show promise for better hair growth in androgenetic alopecia but need more research.

Compound 7b is a promising candidate for treating benign prostatic hyperplasia and prostate cancer.

Alpha-blockers and 5-alpha reductase inhibitors are main treatments for BPH, with new support for phosphodiesterase-5 inhibitors and beta-3 agonists.

Some hair loss and prostate drugs might increase the risk of diabetes and heart disease.

Intralesional corticosteroids and 5-alpha-reductase inhibitors are the best treatments for frontal fibrosing alopecia.