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Steroidogenesis inhibitors change but don't stop androgen production in prostate cancer.

Hormones like testosterone and estrogen significantly affect hair growth and structure.

5-α-reductase inhibitors reduce prostate cancer risk but may cause sexual dysfunction and don't affect high-grade tumor or death rates.

Finasteride irreversibly affects human steroid 5α-reductase 2, providing insight into its catalytic mechanism and disease-related mutations.

Men taking dutasteride or finasteride have a slightly higher risk of developing type 2 diabetes.

Finasteride doesn't affect sleep spindles in men.

Finasteride raises suicide-linked aggression and stops clozapine's positive effects in schizophrenia animals.

Young girls whose mothers have PCOS may have higher activity of a specific enzyme that could lead to developing PCOS later.

Dutasteride reduces DHT more effectively than finasteride.

5α-Reductase inhibitors do not consistently increase testosterone levels in the blood.

Finasteride exposure in pregnancy causes genital abnormalities in male rats.

5α-reductase inhibitors can cause sexual problems, higher risk of aggressive prostate cancer, and depression.

Finasteride and dutasteride effectively treat hair loss, but may cause side effects like sexual dysfunction and depression.

Men taking 5α-reductase inhibitors for enlarged prostate have a higher chance of experiencing reduced sexual desire and erectile dysfunction.

Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.

Special nanoparticles increased skin absorption of hair loss treatments with fewer side effects.

Finasteride effectively reduces hair growth in women with idiopathic hirsutism, but requires careful contraception during treatment.

Using finasteride or dutasteride may cause long-lasting erectile dysfunction.

Finasteride temporarily lowers male rat fertility without affecting libido.

Avicequinone C, a compound found in the Avicennia marina plant, can reduce hair loss by inhibiting a hormone linked to androgenic alopecia.

5α-reductase inhibitors like finasteride may not be effective or safe for transgender individuals, and more research is needed.

Dutasteride may help shrink prostate cancer tumors.

Low dose finasteride decreases certain steroids, possibly increasing depression risk.

High doses of finasteride cause cell growth and tumors in mice.

Finasteride causes abnormal growth in male mice cells at high doses.

Glioblastoma cells can make androgens, which might help the tumor grow.

Male yak hair growth is influenced by DHT synthesis, which is promoted by 5α-red1 and AR during growth phases, while E2 may inhibit growth through ERα.

Androgen treatment with dihydrotestosterone may help maintain height in patients with 5-α-reductase type 2 deficiency, especially before puberty.

Dutasteride may help treat prostate cancer by causing cancer cells to shrink and die.

Finasteride and dutasteride effectively treat hair loss in men and women, but may cause side effects like low libido and depression.