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The document concludes that developing generic topical drugs requires ensuring they match the original in quality, composition, and structure, and often involves complex testing and regulatory steps.

Hormone treatments in transsexual individuals reduce hair growth and oil production in male-to-females and increase them in female-to-males.

Methotrexate treats various disorders by inhibiting DNA synthesis, but careful monitoring is needed to avoid toxicity and manage side effects.

Androgens, like testosterone, are crucial for early testicular descent in rats.

Liposomes and niosomes improve finasteride delivery for hair loss treatment.

Some drugs can cause skin, nail, and hair problems, which are important for healthcare professionals to recognize and report.

Liposomes could improve how skin care products work but are costly and not very stable.

Stress increases a factor in mice that leads to hair loss, and blocking this factor may prevent it.

Alopecia areata treatment varies, with no optimal method established yet.

Low-oxygen conditions and ECM degradation products increase the healing abilities of perivascular stem cells.

A new mutation in the human glucocorticoid receptor reduces its function and causes resistance to glucocorticoids.

MDP hydrogel heals wounds faster and better than other treatments in diabetic mice.

Stem cells from hair follicles can safely treat hair loss.

The document concludes that rapid identification, isolation, and strict infection control are crucial to manage SARS outbreaks.

The conclusion is that managing androgen excess requires long-term treatment, including hormonal contraceptives and androgen blockers, with follow-up after six months.

Testosterone therapy seems safe for postmenopausal women for a few years, but more research is needed for long-term effects.

Amenorrhea is relatively rare and initial testing should check FSH, TSH, and prolactin levels.

Women with PCOS often have skin problems like excessive hair, acne, hair loss, and dark patches, which can be treated with hormonal and non-hormonal therapies.

Myo-inositol may be more effective than metformin for inducing ovulation in women with PCOS.

Minoxidil helps hair cells live longer and grow longer.

Women with PCOS have different levels of certain fats and proteins in their blood, which could help diagnose the condition.

Some breast cancer chemotherapy can cause permanent hair loss.

Acne is caused by genetics, diet, hormones, and bacteria, with treatments not yet curative.

The document concludes that alopecia areata is an autoimmune disease without a definitive cure, but treatments like corticosteroids are commonly used.

No cure for female pattern hair loss, but various effective treatments exist.

The conclusion is that the best initial treatment for hirsutism is usually oral contraceptives, with the addition of antiandrogens or insulin sensitizers if needed, and topical eflornithine or laser treatments as supplementary options.

Diane 35 plus finasteride is more effective for treating hirsutism.

Squarticles effectively deliver hair growth drugs to follicles and dermal papilla cells.

Low iron and vitamin D levels are linked to hair loss in women.

Sebaceous glands in the skin play a key role in absorbing the antiandrogen drug RU 58841, especially when it's encapsulated in liposomes.