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The report concludes that PCOS is mainly a condition of excess male hormones and its definition may change as new information is discovered.

Adding anti-Müllerian hormone to PCOS criteria lowers the number of women diagnosed.

Electrolysis is effective for permanent hair removal, but technique is key to avoid scarring, and sometimes hormonal treatment is needed for women with hirsutism.

The skin's internal clock affects healing, cancer risk, aging, immunity, and hair growth, and disruptions can harm skin health.

Stress increases nerve fibers and immune cell activity in mouse skin, possibly worsening skin conditions.

Treating psoriasis on the scalp, nails, and skin folds is challenging, often requiring systemic treatments for severe cases, with some success in topical and biologic treatments.

Iranian veterans exposed to sulfur mustard suffer from long-term skin itching and eye damage, with some risk of skin cancer and ongoing management challenges.

Genetic differences may affect COVID-19 deaths; anti-androgens could be potential treatment.

Insulin resistance may contribute to various skin diseases and treating it could improve skin health and prevent more serious conditions.

Metformin combined with lifestyle changes improves insulin resistance and reduces testosterone levels in women with PCOS more than lifestyle changes alone.

The study found that certain microRNAs are higher in the cells and lower in the fluid of women with a specific type of polycystic ovary syndrome, and one microRNA could potentially help diagnose the condition.

DNA variants can predict male pattern baldness, with higher risk scores increasing baldness likelihood.

The document suggests creating a validated score to diagnose Cushing's Syndrome and considers plasma steroid profiling as a simpler diagnostic method.

The French Endocrine Society suggests diagnosing PCOS with two of three signs, recommends lifestyle changes and clomiphene for treatment, and calls for more research on certain treatments and tests.

Some women with PCOS have CYP21 mutations and IRS1 variants, but these genetic factors are not major contributors to PCOS.

Testosterone causes hair loss in AGA mice, which are good for testing baldness treatments, and both minoxidil and cyproterone acetate can prevent this hair loss.

Certain DNA variants can predict straight hair in Europeans but are not highly specific.

Potassium channel openers like minoxidil help hair grow by acting on hair follicles.

Chlormadinone acetate is a strong, well-tolerated hormone used in birth control and hormone therapy with benefits for menstrual pain and skin conditions.

Spironolactone is better than placebo for reducing excessive hair growth in women, but its effectiveness for acne is unclear due to small study sizes.

Skin diseases, especially psoriasis, greatly affect people's quality of life, similar to chronic diseases.

Women with androgen excess, especially those with PCOS, have a much higher risk of heart disease and stroke.

Skin problems can be linked to sexual abuse, requiring careful medical and psychological evaluation.

Herbal compounds like ricinoleic acid, quercetin-3-O-rutinoside, and hinokiflavone may be safe and effective for treating hair loss.

Testing for CAG repeat polymorphism in the androgen receptor gene is not currently recommended for managing hypogonadism.

Daughters of women with PCOS generally experience normal puberty but may have more body hair and different body fat distribution.

Male hormones worsen kidney transplant damage, but blocking them helps.

Men, diabetes, and high inflammation levels lead to higher COVID-19 antibodies.

Nellore cattle have genetic variations linked to their adaptation to tropical environments.

Long-term use of dutasteride for enlarged prostate may worsen blood sugar, cholesterol, and erectile dysfunction.