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The document concludes that the risk of sexual side effects from 5-alpha-reductase inhibitors is low and often temporary, but more research is needed on potential permanent effects.

Finasteride reduces hair growth and is safe for women with excessive hair.

Finasteride treatment in male rats can reduce fertility and affect sperm development in their offspring.

Some vegetables from Northern Thailand show promise for health benefits, including hair loss treatment and antioxidant properties.

Researchers found new potential but less potent rat enzyme inhibitors using a 3D model.

Plant-based compounds might be a promising alternative for prostate cancer treatment with fewer side effects.

Plant-based compounds might be effective, low-side-effect treatments for prostate cancer by blocking a specific enzyme.

New steroid compounds effectively inhibit 5α-reductase and may treat hair loss.

Dutasteride is more effective than Finasteride in reducing prostate size and PSA levels, but both drugs have similar side effects.

Compounds from the plant Mammea siamensis may help treat hair loss.

The herbal hair gel could be a safe hair growth treatment with minimal side effects.

Minoxidil 2% is more effective for female hair loss, but botanicals have fewer side effects.

Testosterone undecanoate safely and effectively increased penis size in male children with 5-alpha-reductase deficiency.

Hair loss drugs may cause sexual issues and infertility in men.

COVID-19 might worsen symptoms and progression of benign prostatic hyperplasia, possibly due to inflammation and metabolic disturbances in the prostate gland. More research is needed to confirm this.

A new method was created to test the effectiveness of Dihydrotestosterone (DHT) inhibitors, like finasteride and dutasteride, in human and fish cells. The results showed fish cells are more sensitive to these treatments, and dutasteride works better than finasteride in all tested cells.

Finasteride potentially treats hair loss by reducing DHT production.

The developed model can predict effective 5-alpha-reductase enzyme inhibitors.

The enzyme that changes testosterone to a stronger form is mostly found in the part of the hair follicle called the dermal papilla.

Certain Chinese herbs, especially Cacumen platycladi, can promote hair regrowth and reduce hair loss-related hormone levels in mice.

The new progesterone derivatives effectively inhibit 5α-reductase and bind to the androgen receptor.

Finasteride reduces movement issues in Parkinson's disease rats.

Animal models are crucial for learning about hair loss and finding treatments.

Testosterone can build muscle and bone without enlarging the prostate when a specific enzyme is blocked.

Hibiscus rosa sinensis may help manage hair loss.

Citrullus colocynthis fruit extract and its compound may help treat enlarged prostate.

Saw palmetto extracts might help treat male hair loss and need more research.

Certain drugs, especially antiandrogens and spironolactone, significantly increase the risk of gynecomastia.

PCOS has a strong genetic basis, but more research is needed to fully understand it.

Female pattern hair loss diagnosed by scalp appearance, treated with combined therapies and targeted approaches.