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Finasteride modifies 5-alpha-reductases through a two-step process, affecting inhibitor potency and possibly causing side effects.

Finasteride doesn't affect erections much, but may decrease libido in men.

Dihydrotestosterone can be made from dehydroepiandrosterone in skin cells without needing testosterone.

People with hair loss may have different levels of certain hormones due to changes in hormone processing.

Testosterone and dihydrotestosterone play a role in women's health issues like excess hair and baldness, and treatments blocking these hormones may help.

Chinese medicine may help treat hair loss by affecting genes and enzyme activity.

The new compound was more effective than finasteride in reducing markers of hair loss and prostate issues in cell tests.

BRL 7660, once studied for male contraception, showed promise as an acne treatment but was not developed further due to competing drugs.

Two new compounds were found to build bone and muscle without affecting reproductive organs and skin oil glands.

Hydrangea serrata extract may promote hair growth and improve hair health.

Plant extracts may help treat hormone-related hair loss.

Saw palmetto may improve urinary symptoms with fewer sexual side effects compared to some medications.

5-alpha reductase inhibitors may cause sexual side effects, breast complications, and other health risks in men with hair loss.

Early treatment of fibrosing alopecia in a pattern distribution may improve outcomes.

Coffee silverskin may be a beneficial and safe ingredient for cosmetics, offering hydration, firmness, and potential hair growth benefits.

Hormones and metabolism play a complex role in prostate enlargement, and more research is needed to improve diagnosis and treatment.

The document concludes that understanding hair follicle biology can lead to better hair loss treatments.

Germacrone from Curcuma aeruginosa may help treat conditions related to male hormones by blocking a specific enzyme.

Men with a certain baldness pattern at age 40-50 may have a higher risk of aggressive prostate cancer.

The study found that the enzyme linked to acne is present in the same areas of both acne-affected and normal skin.

5-Alpha reductase inhibitors are safe long-term but may be outdated for preventing less significant prostate cancer.

Certain natural compounds can block an enzyme linked to prostate enlargement and hair loss, showing potential for new treatments.

Finasteride improves heart function in obese and aging male rats by reducing oxidative stress and p53 protein levels.

The skin's ability to produce hormones is linked to various skin conditions, and better understanding this process could lead to new treatments.

Different drugs for prostate-related urinary symptoms work but have various side effects, and treatment should be tailored to the individual.

Finasteride reduces movement issues in Parkinson's disease rats.

Hair loss drugs may cause sexual issues and infertility in men.

Plumbago zeylanica extract helps hair growth and reduces a hair loss-related enzyme.

The conclusion is that we need more effective hair loss treatments than the current ones, and these could include new drugs, gene and stem cell therapy, hormones, and scalp cooling, but they all need thorough safety testing.

More men are getting benign prostatic hyperplasia, and there are many treatments, from medication to surgery, with new methods being developed.