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The endocannabinoid system affects oil production and inflammation in skin cells.

The document concluded that stem cells are crucial for skin repair, regeneration, and may help in developing advanced skin substitutes.

Aging causes skin stem cells to work less effectively.

Human dermal fibroblasts are the main cells targeted by a virus that can cause a deadly skin cancer, and a certain inhibitor can effectively block this infection.

Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.

Skin-derived precursors in hair follicles come from different origins but function similarly.

Short-chain fatty acids from *Cutibacterium acnes* cause skin inflammation, contributing to acne.

Prolactin affects the production of different keratins in human hair, which could lead to new treatments for skin and hair disorders.

Fat from the body can help improve hair growth and scars when used in skin treatments.

The new dutasteride formula can be applied to the skin, may promote hair growth, and has fewer side effects.

The vitamin D receptor is essential for skin stem cells to grow, move, and become different cell types needed for skin healing.

Certain human skin cells marked by CD44 and ALDH are rich in stem cells capable of long-term skin renewal.

Urokinase, a type of protein, helps skin cells multiply faster, especially in newborn mice.

The protein Par3 is crucial for healthy skin, affecting the skin barrier, cell differentiation, and stem cell maintenance.

KLF4 is important for maintaining skin stem cells and helps heal wounds.

Both human and animal-derived small extracellular vesicles speed up skin healing equally well.

Two-photon microscopy effectively tracks live stem cell activity in mouse skin with minimal harm and clear images.

Wnt proteins from certain skin cells are crucial for normal hair growth and renewal.

Hair and skin can regenerate without bulge stem cells due to other compensating cells.

Nanocarriers could improve how drugs are delivered through the skin but require more research to overcome challenges and ensure safety.

PDCD4 is important for controlling skin cell growth and healing.

Recombinant human epidermal growth factor is versatile, effective, and safe for long-term skin and mucosal treatments.

A hair-growth formula with cystine and thiamin helps protect skin cells against UV damage and improves their growth.

A specific group of slow-growing stem cells marked by Thy1 is crucial for skin maintenance and healing in mice.

Notch1 signaling is crucial for improving wound healing and skin regeneration by affecting stem cell behavior.

The Foxn1(-/-) nude mouse shows disrupted and expanded skin stem cell areas due to high Lhx2 levels.

TGF-alpha is present in sheep and ferret skin and may affect hair growth without directly stimulating cell proliferation.

Recombinant keratin materials may better promote skin cell differentiation than natural keratin.

The document concludes that a complete skin restoration biomaterial does not yet exist, and more clinical trials are needed to ensure these therapies are safe and effective.

MSC-derived exosomes can help treat COVID-19, hair loss, skin aging, and arthritis.