research Regulation of Androgen Receptor and 5α-Reductase in the Skin of Normal and Hirsute Women
The exact cause of increased 5α-reductase activity leading to hirsutism in women is still unknown.
Search
for
Sort by
Research
240-270 / 1000+ results 
research Sex Differences in the Effect of Finasteride on Acute Ethanol Withdrawal Severity in C57BL/6J and DBA/2J Mice
Finasteride reduces alcohol withdrawal severity in male mice but increases it in female mice.
research Azasteroids as Inhibitors of Testosterone 5α-Reductase in Mammalian Skin
Certain 4-azasteroids are effective at blocking the enzyme that processes testosterone in human skin and could help treat acne, excessive hair growth, and male pattern baldness.
research Stimulating Effect of Adrenalectomy on Hair Growth and Melanin Deposition in Black Rats Fed Diets Adequate and Deficient in the Filtrate Factors of Vitamin B1
Adrenalectomy boosts hair growth and melanin in black rats, even with vitamin B¹ deficiency.
research Clinical and Hormonal Effects of the 5 Alpha-Reductase Inhibitor Finasteride in Idiopathic Hirsutism
Finasteride reduces hair growth and is safe for women with excessive hair.
research Comparison of Finasteride and Flutamide in the Treatment of Idiopathic Hirsutism
Finasteride and flutamide both reduce hair growth, but finasteride has fewer side effects.
research Plasma C19 Steroid Sulfate Levels and Indices of Androgen Bioavailability in Female Pattern Androgenic Alopecia
Women with female pattern hair loss have higher levels of certain androgens, suggesting increased androgen exposure to hair follicles.
research Topical Minoxidil Used Before and After Hair Transplantation
Using topical minoxidil before and after hair transplant surgery can reduce shedding and improve hair regrowth.
research Finasteride Inhibits the Disease-Modifying Activity of Progesterone in the Hippocampus Kindling Model of Epileptogenesis
Finasteride worsens seizures in epilepsy rats and speeds up epileptogenesis in mice.
research The Anxiolytic Effect of Pregnancy in Rats Is Reversed by Finasteride
Pregnancy reduces anxiety in rats, but finasteride reverses this effect.
research Alterations in Androgen Conjugate Levels in Women and Men with Alopecia
People with hair loss may have different levels of certain hormones due to changes in hormone processing.
research Dermal Papilla Cells Serially Cultured with Wnt-10b Sustain Their Hair Follicle Induction Activity After Transplantation into Nude Mice
Cells treated with Wnt-10b can grow hair after being transplanted into mice.
research Effects of Finasteride, a 5 Alpha-Reductase Inhibitor, on Circulating Androgens and Gonadotropin Secretion in Hirsute Women
Finasteride reduces dihydrotestosterone, increases testosterone, and may treat hirsutism in women.
research Effects of Finasteride on Chronic and Acute Ethanol Withdrawal Severity in the WSP and WSR Selected Lines
Finasteride reduces alcohol withdrawal severity and anxiety in mice, but may increase withdrawal severity in some cases.
research Solubilities of Flutamide, Dutasteride, and Finasteride as Antiandrogenic Agents in Supercritical Carbon Dioxide: Measurement and Correlation
Flutamide, dutasteride, and finasteride dissolve differently in supercritical carbon dioxide, with dutasteride dissolving the least.
research Relating Neurosteroid Modulation of Inhibitory Neurotransmission to Behavior
Neurosteroids can influence behavior by modulating brain inhibition, with potential for treating psychiatric disorders.
research Neonatal Finasteride Administration Alters Hippocampal α4 and δ GABAAR Subunits Expression and Behavioral Responses to Progesterone in Adult Rats
research N-Acyl Arylsulfonamides as Novel, Reversible Inhibitors of Human Steroid Sulfatase
Scientists found new, better-working inhibitors for a hormone-related enzyme.
research 5α-Reductase Inhibitors
Finasteride effectively treats enlarged prostate and male baldness, improves symptoms of hirsutism in women, but doesn't work for acne, and may delay prostate cancer progression with few side effects.
research Histopathological Insights Into Hair Loss in Cronkhite-Canada Syndrome: Diffuse Anagen-Telogen Conversion Precedes Clinical Hair Loss Progression
Hair loss in Cronkhite-Canada syndrome is reversible by treating the gut issues and doesn't need steroid treatment for the hair itself.
research A Case of Inflammatory Nonscarring Alopecia Associated With the Tyrosine Kinase Inhibitor Nilotinib
A cancer drug called nilotinib might cause hair loss due to inflammation around hair follicles.
research Skin Hyperpigmentation and Increased Angiogenesis Secondary to Vitamin B12 Deficiency in a Young Vegetarian Woman
Vitamin B12 deficiency can cause skin darkening and increased blood vessels, but treatment can improve symptoms.
research Alopecia Areata in a Rhesus Monkey (Macaca Mulatta)
The monkey's hair loss was due to an autoimmune disease, not genetics.
research Urinary Steroids in Women with Androgenic Alopecia
Women with hair loss had higher levels of certain hormones, suggesting a link to a condition like PCOS.
research Antiandrogen Drugs Lower Serum Prostate-Specific Antigen Levels in Hirsute Subjects: Evidence That Serum PSA Is a Marker of Androgen Action in Women
Antiandrogen drugs can reduce PSA levels in women with excess hair, suggesting PSA is a sign of male hormone activity in women.
research Alopecia Universalis Associated with Cutaneous T Cell Lymphoma
Some patients with a type of skin lymphoma can experience a rare, non-scarring hair loss that looks like another hair loss condition but has distinct features.
research Sulforaphane Promotes Murine Hair Growth by Accelerating the Degradation of Dihydrotestosterone
Sulforaphane may help with hair growth by breaking down a hormone that causes hair loss.
research Clinical Review 74: Dermatological Manifestations of Endocrine Disorders
Skin changes can indicate hormonal imbalances and help diagnose endocrine disorders.
research NUDT15 Polymorphism Explains Serious Toxicity to Azathioprine in Indian Patients With Chronic Immune Thrombocytopenia and Autoimmune Hemolytic Anemia: A Case Series
The NUDT15 gene variant causes severe side effects from azathioprine in some Indian patients.
research The Tendency Towards the Development of Psychosexual Disorders in Androgenetic Alopecia According to the Different Stages of Hair Loss: A Cross-Sectional Study
More hair loss leads to higher risk of psychosexual disorders, especially in women.