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Lygodii Spora extract may help treat hair loss by blocking a hair loss-related enzyme and promoting hair growth.

5-alpha reductase inhibitors slightly increase the risk of sexual and mood side effects, and breast growth in men.

5-alpha-reductase inhibitors may cause a low incidence of erectile dysfunction that decreases over time.

Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

Certain compounds, especially those with a propionic substituent, could potentially be new treatments for hair loss and similar disorders.

Using two drugs together, Flutamide and 4-MA, is more effective for blocking male hormones than using each one alone.

New compounds similar to cromakalim were less effective at inhibiting insulin release but improved in solubility and one acted as a calcium entry blocker, not a potassium channel opener.

Researchers developed a method to measure different forms of a drug that could help treat prostate issues and hair loss, and found how these forms behave in animals.

Some patients taking finasteride or dutasteride may have ongoing sexual problems and depression even after stopping the medication.

Testosterone's muscle-building effects do not require its conversion to DHT.

Finasteride affects urinary steroid profiles and can potentially hide steroid abuse in sports drug testing.

A new compound effectively inhibits human 5α-reductase 1.

Scientists made a chemical (compound 4e) that can be applied on skin to reduce oil production, which can help with acne, but it might cause skin sensitivity to light.

A new anti-baldness patch effectively treats hair loss by blocking enzymes linked to the condition.

Finasteride may affect PNMT, causing side effects.

Phaeodactylum tricornutum extract helps hair follicle cells grow by activating the ERK1/2 pathway.

The developed model can predict effective 5-alpha-reductase enzyme inhibitors.

Blocking autophagy increases survival of inner ear hair cells exposed to gentamicin.

Minoxidil affects collagen-related genes, potentially helping treat fibrosis.

Finasteride reduces male rat fertility by causing issues with copulatory plug formation.

High doses of finasteride cause cell growth and tumors in mice.

Finasteride temporarily lowers male rat fertility without affecting libido.

Polycomb Repressive Complex 2 is not needed for hair regeneration.

The PW91 method is best for calculating the basic physical and chemical properties of Finasteride, a drug used for prostate issues and hair loss.

High testosterone to epitestosterone ratio in hair could predict male-pattern baldness.

Procyanidins from grape seeds reduce nerve pain by blocking specific proteins and inflammation.

Taking five small dutasteride capsules is the same as taking one larger capsule.

New compounds were found to help increase hair growth and decrease hair loss.

The document concludes that targeting 5α-reductase, the androgen receptor, and hair growth genes, along with using compounds with anti-androgenic properties, could lead to more effective hair loss treatments.

Steroids, particularly estrogens and 5α-reductase inhibitors, affect blood vessel-related hair growth processes in hair follicle cells.