research Hutchinson-Gilford Progeria Syndrome: Report of 2 Cases and a Novel LMNA Mutation in China
A new genetic mutation linked to Hutchinson-Gilford progeria syndrome was found in China.
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450-480 / 1000+ resultsresearch Identification of Key Genes in Type 2 Diabetes-Induced Erectile Dysfunction Rats with Stem Cell Therapy Through High-Throughput Sequencing and Bioinformatic Analysis
Stem cell therapy affects 15 key genes in rats with diabetes-related erectile dysfunction.
research Genetic and Hormonal Influence on SARS-CoV-2 Infection Susceptibility
Men may be more vulnerable to severe COVID-19 due to genetic and hormonal factors, but more research is needed.
research Trichogenic Effect of Topical Ketoconazole Versus Minoxidil 2% in Female Pattern Hair Loss: A Clinical and Trichoscopic Evaluation
Minoxidil works faster, but ketoconazole is a safer alternative for female hair loss.
research Identifying Long-Term Effects of SARS-CoV-2 and Their Association With Social Determinants of Health in a Cohort of Over One Million COVID-19 Survivors
Long-term effects of COVID-19 can vary over time and are more likely in certain age and gender groups, while race, income, and education levels have little to no impact. Ongoing medical care is needed due to potential complications.
research Effect of Prostaglandin D2 on Hair Follicle Growth and Its Impact on Hair Follicle Stem/Progenitor Cells
Blocking Prostaglandin D₂ may help treat hair loss.
research Multiple Endocrine Defects in Adult-Onset Sprouty1/2/4 Triple Knockout Mice
Removing Sprouty genes in mice causes various hormone-related issues but does not increase cancer risk by one year of age.
research The G-Protein Coupled Receptor Kinase 2 (GRK2) Orchestrates Hair Follicle Homeostasis
GRK2 is essential for healthy hair follicle function, and its absence can lead to hair loss and cysts.
research Baricitinib Demonstrates Rapid Action Within Just 2 Months of Treatment in Severe and Unresponsive Alopecia Areata: A Case Report
Baricitinib quickly improved severe alopecia areata, with almost total hair regrowth in three months.
research Comparison of Intra-Operative Blood Loss in Patients Undergoing Mono-Polar TURP With and Without Pre-Operative 2 Weeks Use of Finasteride
Taking Finasteride before surgery reduces blood loss and surgery time.
research CaBP1 and 2 Enable Sustained CaV1.3 Calcium Currents and Synaptic Transmission in Inner Hair Cells
CaBP1 and CaBP2 are important for maintaining hearing by supporting continuous calcium currents and nerve signaling in the ear.
research CaBP1 and 2 Enable Sustained CaV1.3 Calcium Currents and Synaptic Transmission in Inner Hair Cells
CaBP1 and CaBP2 are important for continuous hearing by preventing inactivation of calcium currents in ear cells, with CaBP2 also able to restore hearing when reintroduced.
research Alopecia With Vitamin D-Dependent Rickets Type 2A: A Case Report
A child with a rare vitamin D-resistant condition improved with treatment.
research Efficacy and Safety of Topical 5% Azelaic Acid Solution Versus 2% Minoxidil Solution in the Treatment of Female Pattern Hair Loss
5% Azelaic acid is as effective as 2% Minoxidil for female pattern hair loss and could be an alternative for those allergic to Minoxidil or pregnant.
research Surgical Approaches for Repigmenting Vitiligo 2.0
Assessing CD8+ T cell levels before surgery may improve vitiligo treatment outcomes.
research Telogen Effluvium Therapy in SLE with 2% Minoxidil and Oral Antioxidants: A Case Report
Minoxidil and oral antioxidants helped improve hair growth in a patient with hair loss due to lupus.
research The Role of Testosterone in SARS-CoV-2 Infection
Low testosterone levels may lead to more severe COVID-19 outcomes.
research Identifying Long-Term Effects of SARS-CoV-2 and Their Association with Social Determinants of Health in a Cohort of Over One Million COVID-19 Survivors
The research found that COVID-19 survivors experienced long-term effects like anemia and hypertension, with age and gender being important factors, but race, income, and education had little to no impact.
research Using Sodium Valproate in Children Under 2 Years of Age: Study in a District Hospital, Dinajpur, Bangladesh
Sodium valproate caused vomiting in 20% of children under 2 years old, with other side effects like hair loss and loss of appetite also noted.
research Hypothyroidism Versus Hyperthyroidism in Two Cats: The Culprit for Miliary Dermatitis Versus Growth Retardation
One cat with low thyroid hormone had growth issues, and another with high thyroid hormone had skin problems; both got better with treatment.
research Structure, Atomic Hirshfeld Surface, Spectroscopic Studies, and Magnetic and Dielectric Properties of New Mixed Solid Solution (NH4)2Mn0.17Cu0.83Cl4·2H2O
The compound (NH4)2Mn0.17Cu0.83Cl4.2H₂O has a specific structure, shows weak magnetism at low temperatures, and undergoes phase changes at high temperatures.
research Registrars And Fellows Update Session 2
The session covered updates on skin treatments, including radiotherapy, imiquimod, acitretin, JAK inhibitors, and strategies for managing rosacea and preventing surgical infections.
research Metformin Induced Hair Loss in Two Cases
research Comparison of Androgenic Alopecia Distribution Among Type 2 Diabetes and Healthy Women in Isfahan City: A Brief Report
research Metabolic disease with autoimmune phenomena: 2 cases of SLE-like disease in young children diagnosed with lysinuric protein intolerance
The document described two cases of young children with lysinuric protein intolerance, a rare metabolic disease, presenting with symptoms resembling systemic lupus erythematosus (SLE). The first case involved a boy with failure to thrive and various symptoms, including hemolytic uremic syndrome-like disease and lupus nephritis, who tested positive for several autoantibodies. The second case was a Turkish girl with polyarthritis, fatigue, diffuse hair loss, and other symptoms, also showing positive autoantibodies. Both children were diagnosed with a lupus-like disease and treated with immunosuppressive therapy. Metabolic studies revealed low serum levels and high urine levels of arginine, lysine, and ornithine, leading to the diagnosis of lysinuric protein intolerance. The second case was confirmed by identifying a new mutation in the SLC7A7 gene.
research Efficacy of a Herbal Drug and Minoxidil 2% Solution for Treating Telogen Effluvium Infection
research Co-Sponsored by the International Society of Hair Restoration Surgery: Live Surgery Workshop XI: Advancing the Industry of Hair Restoration, March 2–5, 2005, Orlando
research Chronic Toxicity Studies of the Potential Cancer Preventive 2-(Difluoromethyl)-dl-ornithine
The study investigated the chronic toxicity of 2-(difluoromethyl)-dl-ornithine, a potential cancer preventive agent, in rats and dogs. In rats, high dosages (400, 800, and 1600 mg/kg) over 52 weeks caused weight loss, increased platelets, alopecia, skin issues, liver necrosis, and gastric inflammation, with 400 mg/kg being the no-effect dose. In dogs, dosages of 50, 100, and 200 mg/kg led to conjunctivitis, hyperkeratosis, alopecia, and cystic intestinal crypts, but a no-effect dose was not identified. Despite these toxicities, the study suggested that lower dosages might minimize adverse effects, supporting further clinical development of the compound.
research Spatial Transcriptome Profiling Reveals TGFβ-2 in Hair Follicle Progenitor Cells Is a Potential Driver of Androgenetic Alopecia
research Comparison Between 5% Minoxidil Plus 2% Flutamide Solution vs. 5% Minoxidil Solution in the Treatment of Androgenetic Alopecia
Using both minoxidil and flutamide together is more effective for treating hair loss than using minoxidil alone.