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Finasteride effectively blocks rat enzymes, but with varying methods and strength.

Inherited ichthyoses cause widespread skin scaling and thickening due to gene mutations.

All three treatments reduce hirsutism, but spironolactone works best long-term.

Antiandrogens, particularly flutamide and CPA, are most effective for treating hirsutism, with long-term use needed for best results.

Natural 5α-reduced glucocorticoids might be anti-inflammatory with fewer side effects than current options.

Menopause significantly reduces skin collagen, leading to thinner, less elastic skin, and hormone replacement may help but requires careful consideration.

PCOS is a complex disorder managed by treating symptoms and requires a team of specialists.

Certain inhibitors can potentially treat prostate cancer and other hormone-dependent conditions by controlling sex hormone levels in cells.

The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.

Levodopa for Parkinson's disease might be linked to skin issues like melanoma, but it's unclear if the drug or the disease causes them.

The document concludes that sex hormones are crucial for mammalian reproduction, health, and behavior, and require more research for therapeutic use.

Get head MRI for babies with achondroplasia early, use free immunoglobulin light chains to detect certain neurodevelopmental disorders, and video calls work for speech therapy in patients with facial anomalies.

A 3-year-old with vitamin D-resistant rickets and severe hair loss died despite treatment, highlighting the need for improved management of the condition.

There are many treatments for common hair loss, but more trials are needed to decide which are best.

Nutrease powder, a high-protein, low-carb supplement, can help manage Polycystic Ovary Syndrome symptoms, regulate periods, improve ovulation, and restore fertility.

The conclusion is that endocrinology significantly impacts medicine with various common medications used for treatment.

The vitamin D receptor is crucial for bone health and affects various body systems, with mutations potentially leading to disease.

Vitiligo is a skin condition causing white spots, more common in women, often starts before age 20, and can affect mental health.

Cushing's syndrome can cause serious health problems, and early treatment is crucial, but some issues may remain after treatment.

Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

Chemicals and body size might change when puberty starts and progresses, but more research is needed to confirm this.

Vitamin D receptor interacts with certain dietary components to help prevent diseases and regulate hair growth.

Hair loss in women is genetic, diagnosed by examination and biopsy, and treated with minoxidil, finasteride, or transplantation.

Insulin resistance and obesity are key factors in the development and worsening of polycystic ovary syndrome, and lifestyle changes are important for managing it.

Minoxidil and finasteride treat hair loss in men, while minoxidil treats hair loss in women.

Metformin helps manage polycystic ovary syndrome by improving insulin resistance and ovulation, but more research is needed on its full effects.

Skin cells produce and activate vitamin D, which regulates skin functions and supports hair growth.

Menopause can lead to skin and hair problems due to hormonal changes, but hormone replacement therapy might help slow these effects.

The conclusion is that PCOS is caused by ovarian sensitivity to hormones and disrupted hormone control, possibly due to ovarian factors, and more research is needed.

Melatonin helps regulate hair growth and protects the hair follicle from stress.