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Finasteride use changes brain chemicals, causing lasting sexual issues and anxiety/depression.

S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.

Finasteride can slow hair loss and promote growth in postmenopausal women.

New genes and pathways are important for testosterone production and male sexual development.

SAHA syndrome is a condition in women involving skin and hair issues, often related to hormonal imbalances, and is treated based on the underlying cause.

PCOS affects women's health by increasing the risk of diabetes, heart disease, and reproductive issues.

Acne is caused by genetics, diet, hormones, and bacteria, with treatments not yet curative.

Advanced nanocarrier and microneedle drug delivery methods are more effective, safer, and less invasive for treating skin diseases.

Tissue-resident memory T cells can protect against infections and cancer but may also contribute to autoimmune diseases.

An imbalance between certain immune cells is linked to a chronic skin condition and may be influenced by obesity, smoking, and autoimmune issues.

Certain immune system proteins are important for skin healing but can cause problems if there are too many of them.

Dienogest combined with ethinylestradiol is a highly effective birth control that improves menstrual symptoms and has manageable side effects.

Topical JAK inhibitors may help treat some skin conditions but need more research.

Hair sensitivity to androgens is partly controlled by specific enzyme expressions in different hair areas.

Improving insulin sensitivity and weight loss can help manage polycystic ovary syndrome (PCOS).

People with alopecia areata have more Th17 cells and fewer Treg cells, which may be key to the condition's development.

PCOS is often linked to insulin resistance and obesity, and weight loss can improve symptoms.

RTA 408 cream protects mice from radiation skin damage.

Finasteride affects brain and blood steroids, causing lasting sexual and emotional side effects.

Finasteride almost fully depletes allopregnanolone in rat brains and enhances 20α-DHP, but doesn't change 3α-DHP levels.

Lymphocytes, especially CD8+ T cells, play a key role in causing alopecia areata, and targeting them may lead to new treatments.

Polycystic Ovary Syndrome is linked to higher risk of hypertension and heart disease.

Insulin resistance contributes to hormone imbalances in many women with polycystic ovary syndrome.

There are still challenges in diagnosing and treating chronic skin diseases, but there is hope for future improvements.

People with polycystic ovary syndrome have a higher chance of having chronic thyroiditis.

Different types of androgens bind differently to two receptors, AR1 and AR2, in Atlantic croaker's brain and ovarian tissues, suggesting these receptors may control different androgen actions in fish.

The document concludes that the skin's immune system is complex, involving interactions with hair follicles, nerves, and microbes, and can protect or cause disease, offering targets for new treatments.

Androgens play a complex role in skin conditions like acne and hair loss in women, and normal blood levels don't always show true androgen status.

All three treatments reduce hirsutism, but spironolactone works best long-term.

Antiandrogens, particularly flutamide and CPA, are most effective for treating hirsutism, with long-term use needed for best results.