Eating healthy, exercising, and certain nutrients like myoinositol and omega-3s can help manage PCOS symptoms.
December 2020 in “Current Sexual Health Reports” Finasteride can have lasting negative effects on brain function and behavior by disrupting neurosteroid production.
Chrysanthemum zawadskii extract may help treat hair loss by promoting hair growth and affecting growth factors.
August 2012 in “Pharmaceutical Medicine” The document concludes that various medications and treatments can have significant, sometimes adverse, effects on health outcomes.
July 1997 in “Journal of Cutaneous Medicine and Surgery” Finasteride significantly increases scalp hair and prevents hair loss in young and middle-aged men.
212 citations,
May 2012 in “Genes & Development” Planarian regeneration begins with a specific gene activation caused by injury, essential for healing and tissue regrowth.
195 citations,
November 2019 in “Clinica Chimica Acta” High levels of male hormones, insulin resistance, and obesity are closely linked and worsen polycystic ovary syndrome, but more research is needed to improve treatments.
184 citations,
December 2018 in “Nature Communications” Researchers created human hair follicles using a new method that could help treat hair loss.
157 citations,
December 2015 in “Journal of the American Academy of Dermatology” A man with vitiligo and alopecia saw quick skin and hair improvement with ruxolitinib, but skin color gains were lost after stopping treatment.
130 citations,
August 2020 in “Drug Design Development and Therapy” Nanoparticles can improve skin drug delivery but have challenges like toxicity and stability that need more research.
128 citations,
February 2016 in “British Journal of Dermatology” Alopecia areata significantly lowers the quality of life, especially in emotional and mental health aspects.
111 citations,
March 2012 in “Expert Opinion on Drug Delivery” Liposomes could improve how skin care products work but are costly and not very stable.
109 citations,
April 2000 in “European Urology” Finasteride lowers risk of urinary issues and surgery by over 50% in 4 years.
106 citations,
April 2010 in “ACS Nano” C60 fullerenes can alter protein function and may help develop new disease inhibitors.
82 citations,
September 2018 in “Nature Communications” A certain smell receptor in hair follicles can affect hair growth when activated by a synthetic sandalwood scent.
82 citations,
February 1989 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism” A three-month treatment with a GnRH agonist significantly lowered androgen levels and 5α-reductase activity in men with benign prostatic hyperplasia.
71 citations,
February 2020 in “Journal of Translational Medicine” Progress has been made in skin and nerve regeneration, but more research is needed to improve methods and ensure safety.
65 citations,
August 2007 in “Experimental Dermatology” Human hair follicles can make and process prostaglandins, which may affect hair growth.
62 citations,
April 2009 in “British Journal of Dermatology” Epidermal stem cells could lead to new treatments for skin and hair disorders.
61 citations,
September 2010 in “Fitoterapia” Extracts from Tridax procumbens L. have strong anti-inflammatory and antioxidant effects and block inflammation-causing enzymes.
58 citations,
January 2013 in “The Journal of Clinical Endocrinology and Metabolism” Obese women with PCOS show a male-like pattern in certain fat tissue gene expressions.
48 citations,
November 1992 in “Clinical Endocrinology” Long-term finasteride use doesn't change bone density or metabolism.
47 citations,
October 2016 in “Molecular and Cellular Endocrinology” Androgens prevent hair growth by changing Wnt signals in cells.
39 citations,
May 2011 in “Human Immunology” Genetics play a role in acne, but how exactly they contribute is not fully understood.
37 citations,
October 2006 in “Steroids” New sulfur-containing steroid analogs show promise for more targeted medical treatments.
36 citations,
September 2019 in “Journal of Herbal Medicine” Herbal nano-formulations show potential for effective skin delivery but need more research.
36 citations,
November 2018 in “BMC plant biology” ROXY proteins help plants respond to nitrate shortage by affecting nutrient sensing and growth.
34 citations,
May 2017 in “Seminars in Reproductive Medicine” Women with PCOS have a higher risk of diabetes, heart problems, certain cancers, and mental health issues, but early treatment can help manage these risks.
32 citations,
June 2015 in “PLOS ONE” Olive leaf compound oleuropein helps grow hair in mice.
32 citations,
December 2009 in “Archives of Dermatological Research” Dihydrotestosterone increases certain inflammatory signals in skin cells, potentially contributing to acne.