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Did you mean Lymphocytic Infiltration?

GlossaryLymphocytic Infiltration

accumulation of immune cells in tissue causing inflammation

Lymphocytic infiltration refers to the accumulation of lymphocytes, a type of white blood cell, in a particular tissue or organ. This often occurs as part of the body's immune response to infection, inflammation, or autoimmune conditions, where the immune system mistakenly attacks healthy cells. In the context of hair and alopecia, lymphocytic infiltration can be seen in conditions like alopecia areata, where the immune system targets hair follicles, leading to hair loss.

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Immunohistochemical Insight Into the Association Between the Collapse of Immune Privilege in the Sweat Gland and Syringotropic Immune Cell Infiltrates in Collagen Diseases

research Immunohistochemical Insight Into the Association Between the Collapse of Immune Privilege in the Sweat Gland and Syringotropic Immune Cell Infiltrates in Collagen Diseases

September 2017 in “Journal of Investigative Dermatology”

The study found that sweat glands normally suppress immune responses, but this is disrupted in certain skin diseases, possibly contributing to their development.

Immune Response Involving the Bulge Region in Addition to Telogen Conversion Contributes to Hair Loss in a Case of Atypical Drug-Induced Hypersensitivity Syndrome

research Immune Response Involving the Bulge Region in Addition to Telogen Conversion Contributes to Hair Loss in a Case of Atypical Drug-Induced Hypersensitivity Syndrome

1 citations, October 2013 in “The Journal of Dermatology”

Hair loss in a drug reaction case involved both a common shedding phase and an immune attack on hair follicle stem cells.

research Phenobarbital

January 2014 in “Reactions Weekly”

A woman experienced unusual hair loss and skin reactions after taking phenobarbital, but her hair grew back after treatment.

Involvement of the Bulge Region with Decreased Expression of Hair Follicle Stem Cell Markers in Senile Female Cases of Alopecia Areata

research Involvement of the Bulge Region with Decreased Expression of Hair Follicle Stem Cell Markers in Senile Female Cases of Alopecia Areata

20 citations, December 2010 in “JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology”

Decreased CD200 in hair follicles may cause immune issues in some alopecia areata cases.

research Use of Trichoscopy for the Diagnosis of Alopecia Areata Coexisting with Primary Scarring Alopecia in a Female Hair Loss Patient

2 citations, March 2019 in “Journal of Dermatology”

Trichoscopy helped diagnose and treat a woman with two different types of hair loss.

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community Diffuse hair loss and scalp biopsies

in Research 692 upvotes 4 months ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

community The Worst Hair Loss Condition You (MAY) have: LPP

in Research/Science 43 upvotes 3 months ago

Lichen Planopilaris (LPP) is an autoimmune condition causing permanent hair loss and fibrosis, often misdiagnosed. Treatments include pioglitazone, topical corticosteroids, anti-inflammatory medication, and Jak inhibitors.

community Lost density 60% all over scalp in 120 days (4months)

in Update 10 upvotes 6 months ago

A user lost 60% hair density in 4 months, started finasteride and microneedling, and has greasy, flaky, yellowish scalp. They are awaiting biopsy results, and another user suggested trying ketoconazole shampoo.