3 citations
,
May 2017 in “Heliyon” This study found that in a neonatal rat model, skin wounding protected against chemotherapy-induced alopecia through IL-1β signaling, making hair follicles more resistant to damage when wounding exposure was timed correctly.
90 citations
,
February 2001 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that interleukin-1 directly induces the expression of keratin 6 in keratinocytes, which is a marker of activation and involved in inflammatory skin responses.
1 citations
,
July 2012 in “Nasza Dermatologia Online” This study found that patients with alopecia areata had significantly higher serum levels of IL-1α compared to healthy controls, with no significant difference observed in IL-1β levels.
2 citations
,
September 2004 in “Experimental Dermatology” This study found that VR1 activation in human hair follicles inhibited hair growth by suppressing proliferation and promoting apoptosis, suggesting VR1 plays an important role in hair growth regulation.
October 2022 in “Faculty of 1000 Research Ltd” This review discusses the roles of various growth factors and cytokines in skin regeneration, highlighting their potential for future therapeutic development, and reports no new experimental findings.