Genetic variations influence how people respond to dutasteride for hair loss, with some benefiting more from finasteride. Dutasteride is effective for most, but geneticdifferences may cause it to be less effective for some.
Minoxidil's effectiveness varies due to geneticdifferences in the SULT1A1 enzyme, affecting how well it converts to its active form, minoxidil sulfate. Hyper-responders may experience rapid hair growth and increased side effects, such as pericardial effusion, even at low doses.
Dutasteride may not effectively stop scalp hair loss and can cause thinning of facial and body hair, including eyebrows. Users suggest considering other causes like autoimmune conditions or vitamin deficiencies and exploring treatments like finasteride or minoxidil.
Switching from topical to oral minoxidil caused prolonged hair shedding without regrowth, leading to the use of both topical and oral minoxidil with oral finasteride. Responses to these treatments vary, emphasizing the need for personalized approaches.