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    GlossaryHair Loss Gene (Alopecia Gene)

    genetic variations linked to increased risk of hair loss

    The term "Hair Loss Gene" refers to specific genetic variations that are associated with an increased risk of hair loss conditions, such as androgenetic alopecia (commonly known as male or female pattern baldness). One well-known gene linked to hair loss is the AR gene, which affects androgen receptor activity and can influence hair follicle sensitivity to hormones like dihydrotestosterone (DHT). Understanding these genetic factors can help in diagnosing and developing targeted treatments for hair loss.

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      a topical anti-androgen with less systemic involvement

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      community Coffee and androgenetic alopecia

      in Research/Science  12 upvotes   1 year ago
      The conversation discusses a claim that avoiding coffee can lead to significant hair regrowth in individuals with androgenetic alopecia. Participants are skeptical, with some sharing personal anecdotes that contradict the claim, and others discussing the potential role of caffeine in hair loss and the effectiveness of other treatments like finasteride and minoxidil.

      community A concise, easy-to-understand post on Androgenic Alopecia theory and its practical applications

      in Research/Science  92 upvotes   2 years ago
      The mechanism of Androgenic Alopecia and practical applications of treatments like Minoxidil, Finasteride, RU58841, dermarolling, scalp massages, anti-fungals, progesterone, estrogen, PPAR-γ activators, reducing oxidative stress, and scalp exercises. It explains why DHT is important in AA and how other factors might be involved such as hypoxia, increased DKK-1 expression, morphological changes to the scalp, skull growth during childhood/puberty, and blood flow.

      community I am a dermatologist with a clinical interest in alopecia. AMA

      in Will treatment work for me?   1 year ago
      In this conversation, 4990 discussed various treatments for hair loss, including oral minoxidil, PRP, transplan, Jak inhibitors, Dutasteride, Finasteride, Olumiant, Ketoconazole, RU58841, microneedling, baricitinib, and CCCA. They recommended scalp biopsies in unclear cases of DUPA, twice weekly to twice daily shampooing for topical minoxidil users, and two sessions spaced one month apart with follow up at month three to determine the effectiveness of PRP treatment.