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Glossary 6-Mercaptopurine

chemotherapy drug that inhibits cancer cell growth

6-Mercaptopurine (6-MP) is a chemotherapy medication used primarily to treat certain types of cancer, such as acute lymphoblastic leukemia (ALL). It works by interfering with the growth of cancer cells, which are then destroyed by the body. 6-MP is also used in the treatment of some autoimmune diseases due to its immunosuppressive properties.

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Research

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research Nutritional therapy versus 6-mercaptopurine as maintenance therapy in patients with Crohn's disease

68 citations , April 2012 in “Digestive and Liver Disease”

This study found that both Elental and 6-mercaptopurine were effective for maintaining remission in Crohn's disease, without a significant difference between them over 24 months.

research The effect of active hexose correlated compound in modulating cytosine arabinoside-induced hair loss, and 6-mercaptopurine- and methotrexate-induced liver injury in rodents

14 citations , August 2009 in “Cancer epidemiology”

This study found that AHCC significantly reduced alopecia caused by Ara-C in neonatal rats and improved liver function affected by 6-MP and MTX in mice.

research Synthesis and anticancer activity evaluation of Novel 6 mercaptopurine derivatives.

January 2015 in “Journals & Books Hosting (International Knowledge Sharing Platform)”

This study synthesized and evaluated five 6-mercaptopurine derivatives for anticancer activity against three cancer cell lines, detailing the promising results of compound 1.

research Methotrexate for induction of remission in ulcerative colitis

53 citations , August 2014 in “Cochrane library”

This review found no evidence supporting the efficacy of methotrexate for inducing remission in active ulcerative colitis compared to placebo or active comparators.

research Methotrexate for maintenance of remission in ulcerative colitis

51 citations , August 2015 in “Cochrane library”

This systematic review reports that there is currently no evidence supporting methotrexate for maintaining remission in ulcerative colitis; further large-scale trials are needed to assess its efficacy and safety.

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Community Join

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community 6 months progress using fin and min

16 upvotes 5 days ago

A 21-year-old has been using a 1mg finasteride and 3mg minoxidil combination pill for 6 months to address hair loss, with noticeable progress on the crown but not the hairline. They are considering additional treatments like microneedling and have experienced low blood pressure as a side effect.

community 6.5 month transplant progress - 2900 grafts … Dutasteride and oral min for 6 years prior … was almost slick bald 6 years ago

7 upvotes 5 days ago

The user had a hair transplant with 2900 grafts after using oral minoxidil and dutasteride for 6 years, which made them a transplant candidate. They saw no improvement after 2 years on medication and waited 4 more years for a transplant.

community 6 Months of treatment fin + min and dut + min

13 upvotes 1 week ago

The user started a hair loss treatment with finasteride and minoxidil, then switched to dutasteride and minoxidil, experiencing increased body hair and reduced alcohol tolerance. They plan to get a hair transplant in 12 months and have received compliments on their eyelashes.

community 6 week shed is over, now give me some regrowth fgs

10 upvotes 1 week ago

The user experienced significant hair shedding after starting 2.5mg oral minoxidil daily, which lasted from week 3 to week 5, but now hopes for regrowth. Other users encouraged patience, suggesting noticeable improvement by the one-year mark.

community 6 MONT 0,5 DUT and oral minoxidil 5 and 6%

40 upvotes 2 weeks ago

The user experienced hair regrowth after six months using 0.5 mg dutasteride and 5 mg oral minoxidil with 6% topical minoxidil. Some users suggested adding microneedling for further improvement.

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Learn

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learn omega-6

learn Omega 3

Is the omega-3 to omega-6 ratio in your diet feeding your hair problem without you knowing? Nutrition sources describe a lopsided omega-6 to omega-3 intake as pro-inflammatory, but no published human study shows that the dietary ratio changes 5-alpha reductase, scalp DHT or hair loss; the one relevant trial tested a commercial omega-3/6 plus antioxidant supplement in 120 women, not a change in dietary fat ratio.

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