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GlossaryLPAR6

protein receptor involved in hair growth and maintenance

LPAR6, also known as Lysophosphatidic Acid Receptor 6, is a protein encoded by the LPAR6 gene. This receptor is involved in cell signaling and plays a crucial role in hair growth and maintenance. Mutations in the LPAR6 gene can lead to conditions like hypotrichosis, a form of hair loss characterized by sparse and fragile hair.

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research Segregation of Incomplete Achromatopsia and Alopecia Due to PDE6H and LPAR6 Variants in a Consanguineous Family from Pakistan

9 citations , July 2016 in “Genes”

Genetic variants in PDE6H and LPAR6 cause vision impairment and hair loss in two Pakistani brothers.

research Molecular mechanism of ligand recognition and activation of lysophosphatidic acid receptor LPAR6

1 citations , January 2025 in “Proceedings of the National Academy of Sciences”

research Isolated Autosomal Recessive Woolly Hair/Hypotrichosis: Genetics, Pathogenesis, and Therapies

9 citations , May 2021 in “JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology”

Topical minoxidil may help treat a rare genetic hair condition with no fully effective treatments yet.

research Molecular Genetics of Alopecias

9 citations , January 2015 in “Current problems in dermatology”

Scientists have found specific genes linked to different hair loss conditions, which could lead to new treatments.

research Inherited Disorders of the Hair

2 citations , January 2013 in “Elsevier eBooks”

The document explains the genetic causes and characteristics of inherited hair disorders.

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