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    Glossary LPAR6

    protein receptor involved in hair growth and maintenance

    LPAR6, also known as Lysophosphatidic Acid Receptor 6, is a protein encoded by the LPAR6 gene. This receptor is involved in cell signaling and plays a crucial role in hair growth and maintenance. Mutations in the LPAR6 gene can lead to conditions like hypotrichosis, a form of hair loss characterized by sparse and fragile hair.

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    Research 30 of 94

    1. Segregation of Incomplete Achromatopsia and Alopecia Due to PDE6H and LPAR6 Variants in a Consanguineous Family from Pakistan Genes · 2016 · 9 citations
    2. Molecular mechanism of ligand recognition and activation of lysophosphatidic acid receptor LPAR6 Proceedings of the National Academy of Sciences · 2025 · 1 citations
    3. Identification and Characterization of a Novel Lysophosphatidic Acid Receptor, p2y5/LPA6 Journal of Biological Chemistry · 2009 · 253 citations
    4. Autotaxin–lysophosphatidic acid– LPA <sub>3</sub> signaling at the embryo‐epithelial boundary controls decidualization pathways The EMBO Journal · 2017 · 44 citations
    5. The β9 Loop Domain of PA-PLA1α Has a Crucial Role in Autosomal Recessive Woolly Hair/Hypotrichosis Journal of Investigative Dermatology · 2012 · 11 citations
    6. Isolated autosomal recessive woolly hair/hypotrichosis: genetics, pathogenesis and therapies 2021 · 9 citations
    7. Molecular Genetics of Alopecias Current problems in dermatology · 2015 · 9 citations
    8. Inherited Disorders of the Hair Elsevier eBooks · 2013 · 2 citations
    9. Genetics of Alopecia Encyclopedia of Life Sciences · 2012
    10. Genetic Mapping Of Hereditary Ectodermal Dysplasias And Hair Loss Genes 2011
    11. Diagnosis and treatment of isolated autosomal recessive woolly hair/hypotrichosis Frontiers in Medicine · 2025
    12. An Autosomal Recessive Woolly Hair/Hypotrichosis Case with LIPH Mutation in a Turkish Patient Indian Journal of Dermatology · 2025
    13. Non-Edg family LPA receptors: the cutting edge of LPA research 2011 · 68 citations
    14. Keratin 71 Mutations: From Water Dogs to Woolly Hair 2012 · 11 citations
    15. Biology and Genetics of Hair Annual Review of Genomics and Human Genetics · 2010 · 89 citations
    16. Identification of 736T>A mutation of lipase H in Japanese siblings with autosomal recessive woolly hair Journal of dermatology · 2011 · 7 citations
    17. Novel splice site mutation in the <i>LIPH</i> gene in a patient with autosomal recessive woolly hair/hypotrichosis: Case report and published work review The Journal of Dermatology · 2018 · 9 citations
    18. A novel homozygous variant in the dsp gene underlies the first case of non-syndromic form of alopecia Archives of Dermatological Research · 2015 · 2 citations
    19. Autosomal Recessive Woolly Hair Caused by LIPH Mutations: A Case Series of Six Chinese Patients Clinical Cosmetic and Investigational Dermatology · 2025
    20. To grow or not to grow: Hair morphogenesis and human genetic hair disorders Seminars in Cell & Developmental Biology · 2013 · 43 citations
    21. Identification of potential key genes and pathways associated with the Pashmina fiber initiation using RNA-Seq and integrated bioinformatics analysis Scientific Reports · 2021 · 36 citations
    22. Hair Loss in Children Current problems in dermatology · 2015 · 24 citations
    23. Prognosis and Management of Congenital Hair Shaft Disorders without Fragility—Part II Pediatric Dermatology · 2016 · 14 citations
    24. Computational derivation of a molecular framework for hair follicle biology from disease genes Scientific Reports · 2017 · 4 citations
    25. <i>DSG4</i> Gene Variants as a Cause of Hypotrichosis in the Child with Severe Atopic Dermatitis: Clinical Case Вопросы современной педиатрии · 2023
    26. LncRNAs regulate the cyclic growth and development of hair follicles in Dorper sheep Frontiers in veterinary science · 2023
    27. 192 MicroRNAs and their regulatory interactions in the human hair follicle Journal of Investigative Dermatology · 2016
    28. Whole-genome SNP genotyping mapped a novel locus for hereditary hypotrichosis on chromosome 2q31.1–q32.2 Journal of Dermatological Science · 2015
    29. Hair growth promoting effects of adipose tissue-derived stem cells Journal of Dermatological Science · 2009 · 81 citations
    30. A missense mutation in the P2RY5 gene leading to autosomal recessive woolly hair in a Syrian patient Journal of Dermatological Science · 2009 · 13 citations