Targeting Potential of Zinc Oxide Nanoparticles and Finasteride-Loaded Nano Lipidic Carriers-Infused Topical Gel: In Vitro and In Vivo Skin Permeation Studies

November 2023

Shweta Ramkar, Preeti K. Suresh

zinc oxide nanoparticles finasteride nano lipidic carriers topical gel androgenic alopecia Carbopol gel skin permeation drug delivery ZnO nanoparticles NLCs hair loss skin absorption

Studysummary In this study, researchers developed a novel gel formulation combining zinc oxide nanoparticles and finasteride-loaded nanostructured lipid carriers, which showed promising results for topical delivery and effective skin penetration, potentially offering a new treatment approach for androgenic alopecia.

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research Novel Iron Oxide Nanocarriers Loading Finasteride or Dutasteride: Enhanced Skin Penetration for Topical Treatment of Alopecia

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research Histological Evaluation of Follicular Delivery of Arginine via Nanostructured Lipid Carriers: A Novel Potential Approach for the Treatment of Alopecia

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research Follicular Delivery of Spironolactone via Nanostructured Lipid Carriers for Management of Alopecia

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research Design and In Vitro Evaluation of Finasteride-Loaded Liquid Crystalline Nanoparticles for Topical Delivery

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This study suggests that finasteride-loaded liquid crystalline nanoparticles could be a viable alternative to oral administration for treating androgenetic alopecia due to their controlled release and skin permeation properties.

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research Dermal Delivery of Topically Applied Oligonucleotides via Follicular Transport in Mouse Skin

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research Finasteride in the Treatment of Men with Androgenetic Alopecia

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In male pattern hair loss, this study found that finasteride 1 mg daily significantly slowed hair loss and increased hair growth over two years compared to placebo.