Comparative Transcriptome Analysis of the Regenerating Zebrafish Telencephalon Reveals Key Pathways During Early Stages and Activation of Wnt/β-Catenin Signaling

    October 2020 in “ Frontiers in Cell and Developmental Biology ”
    Yeliz Demirci, Gokhan Cucun, Yusuf Kaan Poyraz … Günes Özhan
    Studysummary In this study, researchers found that during zebrafish telencephalon regeneration, the lesioned hemisphere showed distinct gene expression changes and activated Wnt/β-catenin signaling early after injury, suggesting this pathway's significant role in recovery.
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    Research cited in this study 3

    1. Myocardial NF-κB Activation Is Essential for Zebrafish Heart Regeneration Proceedings of the National Academy of Sciences of the United States of America · 2015
    2. Wnt Signaling and Injury Repair Cold Spring Harbor Perspectives in Biology · 2012
    3. Wnt-Dependent De Novo Hair Follicle Regeneration in Adult Mouse Skin After Wounding Nature · 2007