Increased Expression of Psoriasin (S100A7) and Interleukin 17 (IL-17) in Lesional Skin in Lichen Planopilaris

    January 2024 in “ Advances in Dermatology and Allergology ”
    Agnieszka Otlewska-Szpotowicz, Wojciech Baran, Zdzisław Woźniak … Aleksandra Batycka-Baran
    Studysummary This study suggests a potential role for S100A7 and IL-17 in the pathogenesis of lichen planopilaris.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
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    Research cited in this study 17

    1. IL-17 Expression in Perifollicular Fibrosis in Biopsies from Lichen Planopilaris The American Journal of Dermatopathology · 2022
    2. Lichen Planopilaris: First Biopsy Layer Microbiota Inspection PLOS ONE · 2022
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    4. Common Causes of Hair Loss: Clinical Manifestations, Trichoscopy, and Therapy Journal of the European Academy of Dermatology and Venereology · 2020
    5. The IL-23/IL-17 Pathway in Inflammatory Skin Diseases: From Bench to Bedside Frontiers in immunology · 2020
    6. Alopecia Areata Is Characterized by Dysregulation in Systemic Type 17 and Type 2 Cytokines, Which May Contribute to Disease-Associated Psychological Morbidity British journal of dermatology/British journal of dermatology, Supplement · 2019
    7. Frontal Fibrosing Alopecia: An Update on the Hypothesis of Pathogenesis and Treatment International Journal of Women's Dermatology · 2019
    8. Feature Characterization of Scarring and Non-Scarring Types of Alopecia by Multiphoton Microscopy Lasers in Surgery and Medicine · 2018
    9. IL-17 Inhibition: Is It the Long-Awaited Savior for Alopecia Areata? Archives of Dermatological Research · 2018
    10. Therapeutic management of classic lichen planopilaris: a systematic review Clinical Cosmetic and Investigational Dermatology · 2018
    11. Treatment of Frontal Fibrosing Alopecia and Lichen Planopilaris: A Systematic Review Journal of the European Academy of Dermatology and Venereology · 2013
    12. Alopecia Areata: An Autoimmune Disease Causing Hair Loss The New England Journal of Medicine · 2012
    13. Histopathology of Alopecia Areata, Acute and Chronic: Why Is It Important to the Clinician? Dermatologic Therapy · 2011
    14. Significance of the S100A4 Protein in Psoriasis Journal of Investigative Dermatology · 2009
    15. Lichen Planopilaris: Update on Diagnosis and Treatment Seminars in Cutaneous Medicine and Surgery · 2009
    16. Lichen Planopilaris: Chronic Scarring Alopecia with Autoimmune Component Dermatologic therapy · 2008
    17. Frontal Fibrosing Alopecia Versus Lichen Planopilaris: A Clinicopathological Study International Journal of Dermatology · 2006