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Glossary Psoriasis

chronic autoimmune condition causing rapid skin cell buildup and scaling

Psoriasis is a chronic autoimmune condition that causes the rapid buildup of skin cells, leading to scaling on the skin's surface. This buildup forms red patches covered with silvery scales, often accompanied by itching and pain. The most common type is plaque psoriasis, also known as psoriasis vulgaris, which typically appears on the elbows, knees, scalp, and lower back. The exact cause is unknown, but it involves a combination of genetic, environmental, and immune system factors.

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Research

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Non-Invasive Approaches for the Diagnosis of Autoimmune/Autoinflammatory Skin Diseases: A Focus on Psoriasis and Lupus Erythematosus

research Non-invasive Approaches for the Diagnosis of Autoimmune/Autoinflammatory Skin Diseases—A Focus on Psoriasis and Lupus erythematosus

17 citations , August 2019 in “Frontiers in Immunology”

This review examines non-invasive methods for diagnosing inflammatory skin diseases like lupus erythematosus and psoriatic inflammation using samples from plucked hair and skin tape-strips, but no new clinical results are presented.

research Increased expression of psoriasin (S100A7) and interleukin 17 (IL-17) in lesional skin in lichen planopilaris

2 citations , January 2024 in “Advances in Dermatology and Allergology”

This study suggests a potential role for S100A7 and IL-17 in the pathogenesis of lichen planopilaris.

research Psoriasis and psoriatic arthritis patient productivity burden in the United States

April 2012 in “Journal of the American Academy of Dermatology”

This study found that psoriasis patients had a significantly higher prevalence of autoimmune diseases and other comorbidities compared to those without psoriasis.

research Egr-1 is main key regulator in IL-17F-induced psoriasin expression in human keratinocytes

April 2012

This study found that patients with psoriasis had a significantly higher prevalence of autoimmune diseases and other comorbidities compared to individuals without psoriasis.

research Prevalence of autoimmune diseases and other comorbidities in patients with psoriasis in the United States

April 2012

This study found that patients with psoriasis have a significantly higher prevalence of autoimmune diseases and other physical and mental comorbidities compared to those without the condition.

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Community Join

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community Scalp Psoriasis and Fin/Min options?

in Treatment 3 upvotes 8 months ago

A user with scalp psoriasis and hair loss is hesitant to use topical minoxidil and finasteride due to concerns about psoriasis and potential side effects. They are considering alternatives like pumpkin seed and saw palmetto.

community 33M Medication w/scalp psoriasis

in Progress Pictures 1 upvotes 4 months ago

A 33-year-old male restarted finasteride after stopping it to conceive, noticing hair loss, especially in the crown area. His current routine includes finasteride, minoxidil, ketoconazole, and microneedling, and he plans to continue this treatment for 18 months before making any major changes.

community Scalp Inflammation Beyond Psoriasis: A Hidden Player in Hair Thinning

in Technology 54 upvotes 4 months ago

Scalp inflammation may contribute to hair thinning, with treatments like ketoconazole shampoo potentially helping by reducing inflammation. Some users report that DHT blockers and other treatments like finasteride, minoxidil, and RU58841 can alleviate symptoms associated with inflammation.

community Stopping min on scalp - psoriasis

in Minoxidil 35 upvotes 1 year ago

A user with mild psoriasis on the scalp is using finasteride, topical minoxidil, and dermarolling for hair loss but plans to stop minoxidil on the crown due to psoriasis aggravation. Suggestions include switching to a lipid-based minoxidil, using Ketoconazole shampoo, or trying oral minoxidil.

community Tropical Dut 0.5 and Scalp Psoriasis

1 upvotes 5 months ago

The user reports that using topical Dutasteride has stopped their hair loss, and they are curious about potential side effects and regrowth. They also mention having scalp psoriasis and past SSRI use affecting libido.

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Learn

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learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

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