Search
for

    Did you mean Psoriasis?
    Glossary Psoriasis

    chronic autoimmune condition causing rapid skin cell buildup and scaling

    Psoriasis is a chronic autoimmune condition that causes the rapid buildup of skin cells, leading to scaling on the skin's surface. This buildup forms red patches covered with silvery scales, often accompanied by itching and pain. The most common type is plaque psoriasis, also known as psoriasis vulgaris, which typically appears on the elbows, knees, scalp, and lower back. The exact cause is unknown, but it involves a combination of genetic, environmental, and immune system factors.

    Related Terms

    Sort by

    Research 30 of 1000+

    1. Non-invasive Approaches for the Diagnosis of Autoimmune/Autoinflammatory Skin Diseases—A Focus on Psoriasis and Lupus erythematosus Frontiers in Immunology · 2019 · 17 citations
    2. Increased expression of psoriasin (S100A7) and interleukin 17 (IL-17) in lesional skin in lichen planopilaris Advances in Dermatology and Allergology · 2024 · 2 citations
    3. Psoriasis and psoriatic arthritis patient productivity burden in the United States Journal of the American Academy of Dermatology · 2012
    4. Egr-1 is main key regulator in IL-17F-induced psoriasin expression in human keratinocytes 2012
    5. Prevalence of autoimmune diseases and other comorbidities in patients with psoriasis in the United States 2012
    6. Anti-TNF antibody-induced psoriasiform skin lesions in patients with inflammatory bowel disease are characterised by interferon-γ-expressing Th1 cells and IL-17A/IL-22-expressing Th17 cells and respond to anti-IL-12/IL-23 antibody treatment Gut · 2013 · 278 citations
    7. Role of regulatory T cells in psoriasis pathogenesis and treatment British Journal of Dermatology · 2020 · 273 citations
    8. Generalized Pustular Psoriasis Archives of Dermatology · 1991 · 143 citations
    9. Psoriasis of the Scalp American Journal of Clinical Dermatology · 2001 · 128 citations
    10. Animal Models of Psoriasis – What Can We Learn from Them? Journal of Investigative Dermatology · 1999 · 127 citations
    11. The histopathologic spectrum of psoriasis Clinics in Dermatology · 2007 · 111 citations
    12. Psoriasis treatment in difficult locations: scalp, nails, and intertriginous areas Clinics in Dermatology · 2008 · 104 citations
    13. A polygenic mouse model of psoriasiform skin disease in CD18-deficient mice. Proceedings of the National Academy of Sciences · 1996 · 89 citations
    14. A review of acitretin, a systemic retinoid for the treatment of psoriasis Expert Opinion on Pharmacotherapy · 2005 · 75 citations
    15. Psoriatic Alopecia/Alopecia Areata–Like Reactions Secondary to Anti–Tumor Necrosis Factor-α Therapy: A Novel Cause of Noncicatricial Alopecia The American Journal of Dermatopathology · 2011 · 72 citations
    16. Sebaceous Gland Atrophy in Psoriasis: An Explanation for Psoriatic Alopecia? Journal of Investigative Dermatology · 2016 · 69 citations
    17. Keratinocyte differentiation in psoriatic scalp: morphology and expression of epithelial keratins British Journal of Dermatology · 2006 · 63 citations
    18. Concomitant Vitiligo and Psoriasis in a Patient Treated with Interferon Alfa‐2a for Chronic Hepatitis B Infection Pediatric Dermatology · 2004 · 60 citations
    19. Animal models of psoriasis—highlights and drawbacks 2020 · 53 citations
    20. Loss of epidermal Evi/Wls results in a phenotype resembling psoriasiform dermatitis 2013 · 51 citations
    21. Metabolic syndrome and skin: Psoriasis and beyond Indian Journal of Dermatology · 2013 · 50 citations
    22. The imbalance between Type 17 T-cells and regulatory immune cell subsets in psoriasis vulgaris Frontiers in Immunology · 2022 · 49 citations
    23. Autoimmunity and autoimmune co-morbidities in psoriasis Immunology · 2018 · 49 citations
    24. Anti-TNF-Alpha Induced Psoriasiform Eruptions with Severe Scalp Involvement and Alopecia: Report of Five Cases and Review of the Literature Dermatology · 2012 · 49 citations
    25. Significance of the S100A4 Protein in Psoriasis Journal of Investigative Dermatology · 2009 · 45 citations
    26. In situ detection of retinoid-X receptor expression in normal and psoriatic human skin 1995 · 42 citations
    27. Psoriatic alopecia Clinical and Experimental Dermatology · 2015 · 41 citations
    28. Treatment of Psoriasis vulgaris with a New Retinoic Acid Derivative Ro 10-9359 Dermatology · 1977 · 39 citations
    29. Turner's syndrome associated with psoriasis and alopecia areata Journal of the European Academy of Dermatology and Venereology · 2003 · 37 citations
    30. Metabolic Syndrome Prevalence in Psoriasis American Journal of Clinical Dermatology · 2014 · 32 citations