Effects of Non-Contingent Cocaine on 3alpha-Androstanediol: Disruption of Male Sexual Behavior

    May 2019 in “ Physiology & Behavior ”
    Amy S. Kohtz, Alicia A. Walf, Cheryl A. Frye
    Studysummary This study found that cocaine disrupted the relationship between certain brain androgen levels and sexual behavior in male rats, with dose-dependent effects on testosterone metabolism.
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    Research cited in this study 4

    1. Effects of Subchronic Finasteride Treatment and Withdrawal on Neuroactive Steroid Levels and Their Receptors in the Male Rat Brain Neuroendocrinology · 2015
    2. Androgen Levels and Semen Parameters Among Former Users of Finasteride With Persistent Sexual Adverse Effects JAMA Dermatology · 2014
    3. Adverse Side Effects of 5α-Reductase Inhibitors Therapy: Persistent Diminished Libido, Erectile Dysfunction, and Depression in a Subset of Patients The Journal of Sexual Medicine · 2010
    4. Membrane Androgen Receptors May Mediate Androgen Reinforcement Psychoneuroendocrinology · 2010