3 citations
,
January 2024 in “Frontiers in Endocrinology” This study found that androgen impacted glucocorticoid signaling in the mouse brain only in the prefrontal cortex and substantia nigra, suggesting limited interaction between these hormones at high corticosterone levels.
4 citations
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May 2019 in “Physiology & Behavior” This study found that cocaine disrupted the relationship between certain brain androgen levels and sexual behavior in male rats, with dose-dependent effects on testosterone metabolism.
19 citations
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September 2006 in “Journal of Neurophysiology” In this study, researchers found that after reducing GABAergic inhibition in rats' auditory midbrain, the brain quickly compensates by increasing local neurosteroid synthesis to maintain balance in neural circuits.
36 citations
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July 2005 in “Journal of Neuroendocrinology” This study suggests that both the central biosynthesis and metabolism of progesterone to 3α,5α‐THP in the ventral tegmental area are crucial for facilitating lordosis in female rats.
26 citations
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August 2004 in “Alcoholism Clinical and Experimental Research” This study found that ethanol-induced deficits in motor coordination in rats are not mediated by elevated neuroactive steroid biosynthesis.