Lichen Planopilaris and Low-Level Light Therapy: Four Case Reports and Review of the Literature About Low-Level Light Therapy and Lichenoid Dermatosis

February 2020 in “ Dermatology and therapy ”

Michael Randolph, Waleed Al Salhi, Antonella Tosti

Lichen planopilaris scarring alopecia Low-Level Light Therapy LLLT inflammation hair regrowth LPP light therapy

Studysummary This study reported that four patients with lichen planopilaris showed dramatic improvement, including symptom reduction and hair regrowth, after treatment with low-level light therapy.

Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer

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Research cited in this study

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research Diffuse Variants of Scalp Lichen Planopilaris: Clinical, Trichoscopic, and Histopathologic Features of 40 Patients

35 citations , November 2019 in “Journal of the American Academy of Dermatology”

This study reviewed 40 patients with scalp symptoms and identified a new variant of diffuse lichen planopilaris in 20 individuals, suggesting these conditions should be considered in similar cases.

research Effectiveness of Low-Level Laser Therapy in Lichen Planopilaris

16 citations , December 2017 in “Journal of The American Academy of Dermatology”

This study found that low-level laser therapy may reduce inflammation and increase hair thickness in patients with lichen planopilaris after six months of treatment, though the small sample size limits the findings.

research Novel Treatment Using Low-Dose Naltrexone for Lichen Planopilaris

39 citations , November 2017 in “PubMed”

This case series reported that low-dose naltrexone may benefit patients with lichen planopilaris by reducing scalp symptoms and slowing disease progression, with no adverse effects observed in the patients.

research Primary Cicatricial Alopecia: Treatment Approaches and Classification

95 citations , November 2016 in “Journal of The American Academy of Dermatology”

This article reviews primary cicatricial alopecias, focusing on lymphocytic forms such as chronic cutaneous lupus erythematosus, according to a classification by the North American Hair Research Society, and reports no new clinical results.

research A Case Series of 46 Patients With Lichen Planopilaris: Demographics, Clinical Evaluation, and Treatment Experience

47 citations , June 2014 in “Journal of Dermatological Treatment”

This retrospective review found that while intralesional corticosteroids provided symptomatic improvement for lichen planopilaris, hydroxychloroquine with topical corticosteroids led to higher remission rates but did not result in visible hair regrowth.

research Lichen Planopilaris Is Characterized By Immune Privilege Collapse Of The Hair Follicle's Epithelial Stem Cell Niche

220 citations , June 2013 in “The Journal of Pathology”

This study found that immune privilege collapse in the hair follicle bulge and associated immune responses may contribute significantly to the pathogenesis of lichen planopilaris, suggesting a potential autoimmune basis for the disease.

research Lichen Planopilaris: Update on Diagnosis and Treatment

160 citations , March 2009 in “Seminars in Cutaneous Medicine and Surgery”

This article reviews lichen planopilaris, its presentation, and treatment challenges, and emphasizes the need for more research into its pathogenesis and therapy efficacy; it reports no new findings.