Use of Topical Minoxidil, 17α-Estradiol and Hydrocortisone Butyrate in Frontal Fibrosing Alopecia

    Alberto Rossi, Alberto Orso Maria Iorio, Marco Scarnò, Maria Caterina Fortuna, L. Priolo, D. Di Nunno, Marta Carlesimo, Stefano Calvieri, E. Mari
    Image of study
    TLDR A lotion with minoxidil, hydrocortisone butyrate, and 17a-estradiol can improve or stabilize Frontal Fibrosing Alopecia in some cases, but there's no universally-accepted treatment yet.
    In 2014, a study involving 40 women with Frontal Fibrosing Alopecia (FFA) evaluated the effectiveness of a topical lotion containing minoxidil, hydrocortisone butyrate, and 17a-estradiol. The lotion was applied daily for 36 months. The results showed improvement in 20 patients, stabilization in 15, and worsening in 5. The study concluded that the lotion significantly improved or stabilized FFA, with no observed side effects. However, the study also acknowledged the lack of a universally-accepted treatment for FFA due to its complex nature and incomplete understanding of its causes.
    View this study on →

    Cited in this study