Ultrahigh-Power Sonicator Lysis Enables Deep Proteomic Profiling of Hair Shafts for Fetal Growth Restriction Biomarker Discovery

    November 2025 in “ Analytical Chemistry ”
    Yuhong Hu, Tingyu Hu, Juan Chen … Feng Zhou
    Studysummary This study developed an ultrahigh-power sonicator to improve protein extraction from hair shafts, followed by advanced proteomic analysis, identifying 239 differentially expressed proteins in fetal growth restriction cases compared to healthy controls, which were validated as potential biomarkers for perinatal diagnostics.
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    Research cited in this study 9

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