Topically Applied Magnetized Saline Water Activates Autophagy in the Scalp and Increases Hair Count and Hair Mass Index in Men With Mild-to-Moderate Androgenetic Alopecia

    November 2023 in “ Cureus ”
    Ángel G. Martín, Andrés Santiago Sáez, Manuel Gómez Serrano … Piercarlo Minoretti
    Studysummary In this pilot study, a 12-week topical treatment with a lotion containing magnetized saline water significantly increased hair count and hair mass index while activating autophagy in the scalp of 20 Caucasian men with mild-to-moderate androgenetic alopecia.
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    Research cited in this study 12

    1. Treatment of Androgenetic Alopecia: Current Guidance and Unmet Needs Clinical, Cosmetic and Investigational Dermatology · 2023
    2. Treatment Options for Androgenetic Alopecia: Efficacy, Side Effects, Compliance, Financial Considerations, and Ethics Journal of Cosmetic Dermatology · 2021
    3. Impairment of Autophagy May Be Associated with Follicular Miniaturization in Androgenetic Alopecia by Inducing Premature Catagen Journal of Dermatology · 2020
    4. Physiopathology and Current Treatments of Androgenetic Alopecia: Going Beyond Androgens and Anti-Androgens Dermatologic Therapy · 2019
    5. Hydroxytyrosol Prevents Dermal Papilla Cells Inflammation Under Oxidative Stress by Inducing Autophagy Journal of Biochemical and Molecular Toxicology · 2019
    6. Stimulation of Hair Growth by Small Molecules That Activate Autophagy Cell reports · 2019
    7. Autophagy Is Essential for Maintaining the Growth of a Human Mini-Organ: Evidence from Scalp Hair Follicle Organ Culture PLOS Biology · 2018
    8. A Hypothetical Pathogenesis Model for Androgenic Alopecia: Clarifying the Dihydrotestosterone Paradox and Rate-Limiting Recovery Factors Medical Hypotheses · 2017
    9. Androgenetic Alopecia: A Review Endocrine · 2017
    10. Androgenetic Alopecia: An Update Indian Journal of Dermatology, Venereology and Leprology · 2013
    11. Cross-Section Trichometry: A Clinical Tool for Assessing the Progression and Treatment Response of Alopecia International journal of trichology · 2012
    12. TrichoScan: A Novel Tool for the Analysis of Hair Growth In Vivo Journal of Investigative Dermatology Symposium Proceedings · 2003