Systematic Review of Mesotherapy for the Treatment of Hair Loss
August 2023
in “Journal of Dermatological Treatment”
TLDR Mesotherapy might improve hair growth, but more research is needed to confirm its safety and effectiveness.
Mesotherapy, which involves intradermal injections of therapeutic agents, has been studied as a potential treatment for hair loss disorders like Pattern Hair Loss and Telogen Effluvium. A systematic review of 27 articles, including 10 Randomized Controlled Trials, found that mesotherapy using agents like dutasteride, minoxidil, botulinum toxin A, multivitamins, and a plant-derived polypeptide solution has shown significant improvements in hair growth. However, there is a lack of standardized regimens and some studies reported serious adverse effects, including hair loss at the injection site and scalp melanoma. The treatment is not yet approved by the U.S. FDA or Health Canada. The review concludes that further large-scale, controlled clinical trials are needed to evaluate the utility and safety of mesotherapy for hair loss disorders.
View this study on tandfonline.com →
Cited in this study
research Human Stem Cell Use in Androgenetic Alopecia: A Systematic Review
research Systematic Review of Newer Agents for the Management of Alopecia Areata in Adults: Janus Kinase Inhibitors, Biologics and Phosphodiesterase-4 Inhibitors
New oral treatments for adult hair loss show promise, especially JAK inhibitors, with mild side effects.
research Emerging Drugs for the Treatment of Alopecia Areata
research Recent Modalities in Treatment of Telogen Effluvium: Comparative Study
Both botulinum toxin A and multivitamin mesotherapy effectively treat hair loss, with botulinum toxin A being the better single-session option.
research Current application of mesotherapy in pattern hair loss: A systematic review
Mesotherapy might help with hair loss but more research is needed.
research Dutasteride intralesional microinjections in combination with oral minoxidil vs. oral minoxidil monotherapy in men with androgenetic alopecia: a retrospective analysis of 105 patients
research A preliminary result of adipose derived stem cell treatment for female pattern hair loss
Stem cell treatment improved hair density in female hair loss patient.
research Efficacy of botulinum toxin A injection in the treatment of androgenic alopecia: A Comparative Controlled Study
Botox can effectively treat hair loss with some side effects and high cost, while LC hair serum also shows great results with fewer side effects.
research Two Cases of Paradoxical Nonscarring Alopecia after Mesotherapy with Dutasteride
Two people lost hair unexpectedly after getting a common hair loss treatment with a drug called Dutasteride.
research Frontal edema due to mesotherapy for androgenetic alopecia: A case series
research Clinical, trichoscopic, and folliscopic identification of the impact of metabolic syndrome on the response to intradermal dutasteride 0.02% injection in patients with female pattern hair loss: a prospective cohort study
Metabolic syndrome reduces effectiveness of hair loss treatment.
research “Comparison of QR 678 ® & QR678 ® Neo as monotherapy and as combination therapy with 5% Minoxidil solution and oral Finasteride in the treatment of male androgenetic alopecia—Which is better?”
Combination therapy with QR 678 Neo and 5% Minoxidil is most effective for male hair loss.
research Evaluation of efficacy of intradermal injection therapy vs derma roller application for administration of QR678 Neo ® hair regrowth formulation for the treatment of Androgenetic Alopecia—A prospective study
Intradermal injections improve hair density and thickness better, while derma roller is more convenient.
research Telogen Effluvium – a review of the science and current obstacles
The document concludes that we need more research to understand Telogen Effluvium and find effective treatments.
research Lyophilized growth factor intralesional injection in female pattern hair loss: A clinical and trichoscopic study
Injections improve hair growth, density, and thickness in women safely.
research Intradermal injections with 0.5% minoxidil for the treatment of female androgenetic alopecia: A randomized, placebo‐controlled trial
Injections with 0.5% minoxidil effectively treat female hair loss, increasing hair density and thickness.
research Is there a therapeutic effect of botulinum toxin on scalp alopecia? Physiopathology and reported cases: A systematic review of the literature
Botulinum toxin's effectiveness for treating scalp alopecia is not well-supported due to insufficient data.
research Efficacy of Intralesional and Oral Dutasteride in the Treatment of Androgenetic Alopecia: A Systematic Review
Oral dutasteride works better for hair loss, but has more sexual side effects; intralesional dutasteride is a possible alternative.
research Systematic Review of Platelet-Rich Plasma Use in Androgenetic Alopecia Compared with Minoxidil®, Finasteride®, and Adult Stem Cell-Based Therapy
PRP injections may be a safe, effective alternative for hair loss treatment compared to minoxidil and finasteride.
research Novel drug delivery approaches for the management of hair loss
research Excellent response to mesotherapy as adjunctive treatment in male androgenetic alopecia
Mesotherapy helps treat male hair loss effectively.
research Comparative study between mesotherapy and topical 5% minoxidil by dermoscopic evaluation for androgenic alopecia in male: A randomized controlled trial
research A Permanent Hair Loss in a Patient with Hypersensitivity to Intralesional Triamcinolone Injection
research Scalp melanoma after antihair loss mesotherapy
A woman got melanoma on her scalp after anti-hair loss treatment with injections.
research Mesotherapy with dutasteride in the treatment of androgenetic alopecia
research The Effect of Plasma Rich in Growth Factors on Pattern Hair Loss: A Pilot Study
Treatment with plasma rich in growth factors improved hair density and thickness for hair loss patients.
research Hair loss at injection sites of mesotherapy for alopecia
Mesotherapy for hair loss can sometimes cause more hair loss and scarring.
research Androgenetic Alopecia: An Update Of Treatment Options
Minoxidil is the only FDA-approved topical drug for treating male or female pattern hair loss, and other medications like finasteride and dutasteride can also increase hair growth.
research Neonatal derived mesenchymal stem cell mesotherapy in androgenetic alopecia: a retrospective observational study and review of literature
research Mesotherapy using dutasteride-containing preparation in treatment of female pattern hair loss: photographic, morphometric and ultrustructural evaluation
Dutasteride-containing mesotherapy effectively treats female hair loss, improving density and thickness with minimal side effects.
research Evaluation of the effect of injection of dutasteride as mesotherapeutic tool in treatment of androgenetic alopecia in males
Dutasteride mesotherapy helps treat male hair loss but may harm sperm and sexual function.
research Mesotherapy: What is new?
Mesotherapy shows promise for cellulite and facial rejuvenation but has mixed results for body sculpting and hair loss, with more research needed for safety and effectiveness.
research Mesotherapy in management of hairloss - Is it of any use?
Mesotherapy for hair loss lacks evidence of effectiveness and safety and should not be used without further scientific support.
research Alopecia secondary to mesotherapy
Some people experienced hair loss after mesotherapy treatments for hair loss.
Related
research Evaluation of Hair Regrowth After Minoxidil and Dutasteride Tattooing in Men with Androgenetic Alopecia
Minoxidil-dutasteride tattooing can potentially help regrow hair, especially in men who already have some thin hair.
research Combination therapy with oral minoxidil and dutasteride in the treatment of male patterned baldness: A case report
Using oral minoxidil and dutasteride together can quickly increase hair growth and volume with minimal side effects.
research Role of low dose oral minoxidil in the treatment of hair loss: A review
research Deterioration of scalp environment by exogenous factors and its influence on hair growth promoting effect of minoxidil
research Mesotherapy with dutasteride and minoxidil in treatment of androgenetic alopecia
Dutasteride and minoxidil mesotherapy effectively treats hair loss with minimal side effects.
research Side Effects Related to 5 α-Reductase Inhibitor Treatment of Hair Loss in Women: A Review.
The review found that women using hair loss drugs like finasteride and dutasteride rarely reported sexual side effects.
research 5% Minoxidil: treatment for female pattern hair loss.
![[Effect of minoxidil on hair growth in androgenic alopecia in women].](/images/research/be988a6e-f0a9-4502-b4c5-11b7ec15579c/small/12340.jpg)
research [Effect of minoxidil on hair growth in androgenic alopecia in women].
Minoxidil helps stimulate hair growth and reduce hair loss in women with androgenic alopecia.
research Treatment of Hair Loss
Finasteride and minoxidil are effective for hair loss, but continued research is needed for better treatments.