Evaluation of the effect of injection of dutasteride as mesotherapeutic tool in treatment of androgenetic alopecia in males

    January 2013 in “ Our Dermatology Online
    Nagat Sobhy, Hala M. Aly, Adel El Shafee, Marwa El Deeb
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    TLDR Dutasteride mesotherapy helps treat male hair loss but may harm sperm and sexual function.
    The study evaluated the use of dutasteride as a mesotherapeutic tool in the treatment of male pattern hair loss (MPHL). The results showed that mesotherapy using dutasteride is a good option for treating MPHL, resulting in a reduction or cessation of hair loss and promotion of new hair growth. However, systemic absorption of dutasteride following mesotherapy with its deleterious effect on spermatogenesis is possible, especially with unlimited injections. The effect on sexual function by dutasteride mesotherapy is questionable. Mesotherapy using dutasteride is not recommended in patients seeking pregnancy, patients with borderline or abnormal semenogram, and patients with ejaculatory or erectile dysfunction. Further research is needed to establish the exact changes in hair quality and quantity by dutasteride as mesotherapy on a larger number of patients.
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